plasminn.

Brit.

/ˈplazmɪn/, U.S.

/ˈplæzmən/

Forms: 1800s plasmine, 1800s– plasmin.

Origin: Formed within English, by derivation; modelled on a French lexical item. Etymons: plasma n., -in suffix¹.

Etymology: < plasma n. + -in suffix¹, after French plasmine ( P. S. Denis 1858, in Comptes rendus hebd. de l'Acad. des Sci. 47 997).

Physiology.

1. An extract of blood plasma containing soluble proteins including fibrinogen. Now historical.

ΚΠ

1866 H. Watts Dict. Chem. IV. 662 Plasmin,..applied by Denis (Compt. rend. lii. 1239; Jahresb. 1861, p. 725) to a constituent of the blood to which he supposes the property of spontaneous coagulation to be due... It is soluble in water... The solution..solidifies after a few minutes to a colourless transparent jelly, which by pressure between paper is converted into fibres of fibrin.

1877 M. Foster Text Bk. Physiol. i. i. 17 The coagulation of blood is the result of the conversion of plasmine into fibrin.

1895 New Sydenham Soc. Lexicon Plasmine..is a mixture of at least two bodies, paraglobulin and fibrinogen.

1945 Jrnl. Gen. Physiol. 28 581 The term ‘plasmin’ has been used in the past to designate a fraction of blood obtained by a special salting-out procedure.

2. A proteolytic enzyme which destroys blood clots by breaking down fibrin.

ΘΚΠ

the world > life > biology > substance > process stimulators or inhibitors > other stimulators or inhibitors > [noun]

styptica1400

carrier1844

luciferase1888

luciferin1888

urease1892

peroxidase1899

protease1903

renin1903

phenolase1907

proteinase1907

phytase1908

lecithinase1910

uricase1910

phosphatase1912

prunase1912

phenoloxidase1913

oxytocin1927

phosphomonoesterase1932

androgen1936

phosphorylase1939

slow reacting substance1939

phospholipase1945

plasmin1945

bradykinin1949

nitroreductase1953

cytostatic1964

oncogen1967

autoinducer1968

1945 L. R. Christensen & C. M. Macleod in Jrnl. Gen. Physiol. 28 581 Under this scheme the activated enzyme may be termed ‘plasmin’ in comformity [sic] with common usage for proteases, where the prefix indicates the source of the enzyme, followed by -in.

1962 New Scientist 16 Aug. 344/3 Fibrinolysin, or plasmin, which is available commercially.

1968 R. Passmore & J. S. Robson Compan. Med. Stud. I. xxvi. 16/1 The active enzyme in this system, plasmin, is proteolytic but possesses a preference for fibrin as substrate. It is formed from an inactive soluble blood protein precursor, plasminogen, by the action of plasminogen activator.

1999 R. Deakin Waterlog (2000) ix. 103 Cold water, it was found, also dramatically stimulates the production of plasmin, a powerful enzyme which dissolves blood clots before they can build up to cause heart-attacks or strokes.

This entry has been updated (OED Third Edition, June 2006; most recently modified version published online March 2022).

单词	plasmin
释义	plasminn. Brit. /ˈplazmɪn/, U.S. /ˈplæzmən/ Forms: 1800s plasmine, 1800s– plasmin. Origin: Formed within English, by derivation; modelled on a French lexical item. Etymons: plasma n., -in suffix¹. Etymology: < plasma n. + -in suffix¹, after French plasmine ( P. S. Denis 1858, in Comptes rendus hebd. de l'Acad. des Sci. 47 997). Physiology. 1. An extract of blood plasma containing soluble proteins including fibrinogen. Now historical. ΚΠ 1866 H. Watts Dict. Chem. IV. 662 Plasmin,..applied by Denis (Compt. rend. lii. 1239; Jahresb. 1861, p. 725) to a constituent of the blood to which he supposes the property of spontaneous coagulation to be due... It is soluble in water... The solution..solidifies after a few minutes to a colourless transparent jelly, which by pressure between paper is converted into fibres of fibrin. 1877 M. Foster Text Bk. Physiol. i. i. 17 The coagulation of blood is the result of the conversion of plasmine into fibrin. 1895 New Sydenham Soc. Lexicon Plasmine..is a mixture of at least two bodies, paraglobulin and fibrinogen. 1945 Jrnl. Gen. Physiol. 28 581 The term ‘plasmin’ has been used in the past to designate a fraction of blood obtained by a special salting-out procedure. 2. A proteolytic enzyme which destroys blood clots by breaking down fibrin. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > other stimulators or inhibitors > [noun] styptica1400 carrier1844 luciferase1888 luciferin1888 urease1892 peroxidase1899 protease1903 renin1903 phenolase1907 proteinase1907 phytase1908 lecithinase1910 uricase1910 phosphatase1912 prunase1912 phenoloxidase1913 oxytocin1927 phosphomonoesterase1932 androgen1936 phosphorylase1939 slow reacting substance1939 phospholipase1945 plasmin1945 bradykinin1949 nitroreductase1953 cytostatic1964 oncogen1967 autoinducer1968 1945 L. R. Christensen & C. M. Macleod in Jrnl. Gen. Physiol. 28 581 Under this scheme the activated enzyme may be termed ‘plasmin’ in comformity [sic] with common usage for proteases, where the prefix indicates the source of the enzyme, followed by -in. 1962 New Scientist 16 Aug. 344/3 Fibrinolysin, or plasmin, which is available commercially. 1968 R. Passmore & J. S. Robson Compan. Med. Stud. I. xxvi. 16/1 The active enzyme in this system, plasmin, is proteolytic but possesses a preference for fibrin as substrate. It is formed from an inactive soluble blood protein precursor, plasminogen, by the action of plasminogen activator. 1999 R. Deakin Waterlog (2000) ix. 103 Cold water, it was found, also dramatically stimulates the production of plasmin, a powerful enzyme which dissolves blood clots before they can build up to cause heart-attacks or strokes. This entry has been updated (OED Third Edition, June 2006; most recently modified version published online March 2022). < n.1866
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