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单词 phosphorylate
释义

phosphorylatev.

Brit. /fɒsˈfɒrᵻleɪt/, U.S. /fɑsˈfɔrəˌleɪt/
Origin: Formed within English, by derivation. Etymons: phosphoryl n., -ate suffix3.
Etymology: < phosphoryl n. + -ate suffix3. Compare slightly earlier phosphorylated adj., phosphorylation n.
Biochemistry.
transitive. To introduce a phosphate group into (an organic molecule).
ΚΠ
1928 M. Samec in R. P. Walton Comprehensive Surv. Starch Chem. I. v. 53 After removal of the free phosphoric acid, the substance was phosphorylated with phosphorus oxychloride according to the method of C. Neuberg.
1937 Nature 20 Feb. 309/2 Glucose is rapidly phosphorylated in the cells of the living mucous membrane.
1971 Nature 19 Feb. 529/1 Under the action of phosphorylase kinase it [sc. glycogen phosphorylase] is phosphorylated at one serine residue in each of the four subunits.
2002 Science 18 Jan. 403 Activated EphB proteins..caused the activation of the Src tyrosine kinase, which apparently phosphorylates the NMDA receptor.

Derivatives

phosˈphorylating adj.
ΘΚΠ
the world > matter > chemistry > organic chemistry > chemical processes or reactions > biochemical reactions and processes > [adjective] > of or relating to phosphorylation
phosphorylated1926
phosphorylating1937
1937 Biochem. Jrnl. 31 329 (heading) Competition between phosphorylating enzymes in muscle extract.
1970 R. W. McGilvery Biochemistry x. 197 Racker has..suggested that the non-heme iron..may also be associated with the phosphorylating complex.
1990 Age & Ageing 19 368/2 The elements of the intracellular calcium-buffering system include the mitochondria, the endoplasmic reticulum,..and ATP-linked phosphorylating processes.
This entry has been updated (OED Third Edition, March 2006; most recently modified version published online March 2022).
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