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单词 phenelzine
释义

phenelzinen.

Brit. /fᵻˈnɛlziːn/, /fɛˈnɛlziːn/, U.S. /fəˈnɛlˌzin/, /fɛˈnɛlˌzin/
Forms: 1900s– phenelazine, 1900s– phenelzine.
Origin: Formed within English, by compounding. Etymons: pheno- comb. form, ethyl n., hydrazine n.
Etymology: < pheno- comb. form + el- (representing ethyl n.) + -zine (in hydrazine n.).
Pharmacology.
An antidepressant of the monoamine oxidase inhibitor class.Chemical name: 2-phenethylhydrazine, C6H5CH2CH2NHNH2. A proprietary name for this drug is Nardil n.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > medicine for mental conditions > [noun] > antidepressant > specific drugs
Marsilid1952
iproniazid1953
levallorphan1953
imipramine1958
Tofranil1958
isocarboxazid1959
Marplan1959
Nardil1959
nialamide1959
Niamid1959
phenelzine1959
tranylcypromine1959
Parnate1960
amitriptyline1961
monoamine oxidase inhibitor1962
nortriptyline1962
protriptyline1963
MAOI1965
maprotiline1970
mianserin1970
amoxapine1971
fluoxetine1975
paroxetine1977
Prozac1985
Seroxat1985
1959 Amer. Jrnl. Psychiatry 116 64/1 Twenty-five patients with depression who entered this hospital on the female service were assigned alternately to Phenelzine and ECT.
1971 G. G. Luce Body Time iii. 85 Other drugs sometimes used to combat depression, such as phenelzine, have an opposite effect and shorten the sleep cycle.
1989 Adverse Drug Reactions 8 33 Phenelzine has been reported to increase alertness in patients with narcolepsy.
2001 S. Walton Out of It (2002) v. 219 The monoamine oxidase inhibitors.., the most widely prescribed of which is phenelzine, are absolutely contra-indicated in combination with ecstasy, as indeed they are with other stimulants.
This entry has been updated (OED Third Edition, December 2005; most recently modified version published online March 2022).
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n.1959
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