pempidinen.

Brit.

/ˈpɛmpᵻdiːn/, U.S.

/ˈpɛmpəˌdin/

Origin: Formed within English, by compounding. Etymons: penta- comb. form, methyl n., piperidine n.

Etymology: < pe- (in penta- comb. form) + m- (in methyl n.) + pi- (in piperidine n.) + -dine (in piperidine n.).

Pharmacology.

A liquid piperidine derivative, (CH₃)₅C₅H₅NH (1,2,2,6,6-pentamethylpiperidine), which has been used medicinally (usually in the form of its hydrogen tartrate, a white powder) as a ganglion-blocking agent to treat severe hypertension.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders

Neo-Synephrine1934

Priscol1938

phenylephrine1947

hexamethonium1949

Priscoline1949

methonium1950

hydralazine1952

phentolamine1953

methyldopa1954

pentolinium1954

mecamylamine1955

hydrochlorothiazide1958

pempidine1958

guanethidine1959

hydroflumethiazide1959

thiazide1959

pheniprazine1960

pargyline1961

vasodepressor1961

alpha blocker1965

clonidine1969

prazosin1970

timolol1973

1958 Nature 21 June 1717/2 In the simple..tertiary amine, 1:2:2:6:6-pentamethylpiperidine.., for which the common name pempidine has been suggested, we have a potent ganglion-blocking drug.

1960 Lancet 21 Jan. 143/2 In 1958 a new ganglion-blocking agent, pempidine tartrate, was made available under the trade names of ‘Perolysen’ and ‘Tenormal’.

1994 Brain Res. 649 133/2 The nicotine-induced effect..could be abolished by pempidine, a ganglionic nicotinic antagonist that has been shown to be a non-competitive inhibitor of brain nicotine receptor function.

This entry has been updated (OED Third Edition, September 2005; most recently modified version published online March 2022).

单词	pempidine
释义	pempidinen. Brit. /ˈpɛmpᵻdiːn/, U.S. /ˈpɛmpəˌdin/ Origin: Formed within English, by compounding. Etymons: penta- comb. form, methyl n., piperidine n. Etymology: < pe- (in penta- comb. form) + m- (in methyl n.) + pi- (in piperidine n.) + -dine (in piperidine n.). Pharmacology. A liquid piperidine derivative, (CH₃)₅C₅H₅NH (1,2,2,6,6-pentamethylpiperidine), which has been used medicinally (usually in the form of its hydrogen tartrate, a white powder) as a ganglion-blocking agent to treat severe hypertension. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders Neo-Synephrine1934 Priscol1938 phenylephrine1947 hexamethonium1949 Priscoline1949 methonium1950 hydralazine1952 phentolamine1953 methyldopa1954 pentolinium1954 mecamylamine1955 hydrochlorothiazide1958 pempidine1958 guanethidine1959 hydroflumethiazide1959 thiazide1959 pheniprazine1960 pargyline1961 vasodepressor1961 alpha blocker1965 clonidine1969 prazosin1970 timolol1973 1958 Nature 21 June 1717/2 In the simple..tertiary amine, 1:2:2:6:6-pentamethylpiperidine.., for which the common name pempidine has been suggested, we have a potent ganglion-blocking drug. 1960 Lancet 21 Jan. 143/2 In 1958 a new ganglion-blocking agent, pempidine tartrate, was made available under the trade names of ‘Perolysen’ and ‘Tenormal’. 1994 Brain Res. 649 133/2 The nicotine-induced effect..could be abolished by pempidine, a ganglionic nicotinic antagonist that has been shown to be a non-competitive inhibitor of brain nicotine receptor function. This entry has been updated (OED Third Edition, September 2005; most recently modified version published online March 2022). < n.1958
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