pentamidinen.
/pɛnˈtamᵻdiːn/, U.S. /pɛnˈtæməˌdin/ Pharmacology.
An antiprotozoal drug used chiefly for the treatment of leishmaniasis, trypanosomiasis, babesiosis, and pneumocystis pneumonia.Pentamidine is a basic compound of the diamidine class, 4,4′-(pentamethylenedioxy)-dibenzamidine, C19H24N4O2.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for sleeping sickness
pentamidine1941
1941 J. D. Fulton & W. Yorke in Ann. Trop. Med. & Parasitol. 35 229 The name ‘stilbamidine’ has been given to 4:4′-diamidino stilbene, ‘propamidine’ to 4:4′-diamidino diphenoxy propane, ‘pentamidine’ to 4:4′-diamidino diphenoxy pentane, and ‘phenamidine’ to 4:4′-diamidino diphenyl ether.
1951 A. Grollman Pharmacol. & Therapeutics xx. 417 This led to the trial of other diamidine derivatives of which stilbamidine, propamidine and pentamidine are most widely used.
1977 Lancet 3 Sept. 510/2 A man of 66 with non-Hodgkin's lymphoma was suspected of having Pneumocystis carinii infection, and pentamidine was given for 5 days.
2001 N. Jones Rough Guide Trav. Health ii. 250 For severe infections [sc. babesiosis], drugs like chloroquine or pentamidine have been used with limited success.
This entry has been updated (OED Third Edition, September 2005; most recently modified version published online March 2022).
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