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单词 patulin
释义

patulinn.

Brit. /ˈpatjᵿlɪn/, U.S. /ˈpætʃəl(ə)n/
Origin: A borrowing from Latin, combined with an English element. Etymons: Latin patulum , -in suffix1.
Etymology: < scientific Latin patulum, specific epithet of Penicillium patulum (G. Bainier 1909, in Bull. de la Soc. Mycologique de France 25 111; < classical Latin patulum , neuter of patulus : see patulous adj.) + -in suffix1 (compare quot. 1943.
Biochemistry.
A heterocyclic antibiotic compound, C7H6O4, which has carcinogenic properties and is obtained from any of several moulds (originally from Penicillium patulum).It was later found to be identical with clavacin (also called clavatin, claviformin).
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > antibiotics > [noun] > penicillin > other penicillin antibiotics
citrinin1931
griseofulvin1939
patulin1943
procaine penicillin1949
celbenin1960
methicillin1961
amoxicillin1971
1943 H. Raistrick in Lancet 20 Nov. 625/1 A metabolic product of Penicillium patulum Bainier..was isolated and shown to have antibacterial properties; it has now been identified as anhydro-3-hydroxymethylene-tetrahydro-γ-pyrone-2-carboxylic acid, and has been given the shorter name of ‘patulin’.
1950 L. E. Hawker Physiol. Fungi viii. 275 Other species of Penicillium produce other antibiotic substances, such as citrinin.., penicillic acid..and claviformin (patulin or clavacin).
1965 New Scientist 28 Oct. 253/2 He also worked out the structure of the remarkable mould product patulin, which, because of its unusual properties, was at that period a substance of considerable interest.
1995 Daily Tel. 9 Aug. 5/1 People were warned last night not to drink five brands of apple juice that have been contaminated by high levels of patulin, a cancer-causing chemical generated by rotting apples.
This entry has been updated (OED Third Edition, June 2005; most recently modified version published online March 2022).
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n.1943
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