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单词 parachromatin
释义

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parachromatin
parachromatin n.
Brit. /ˌparəˈkrəʊmətɪn/
,
U.S. /ˌpɛrəˈkroʊmədən/
[ < para- prefix1 + chromatin n., after German Parachromatin (W. Pfitzner 1883, in Arch. f. mikroskop. Anat. 22 619)] (a) Cell Biology an achromatic substance of a nucleus (now rare); (b) Genetics (R. A. Brink's name for) the regulatory, as opposed to the structural, components of a chromosome.
ΚΠ
1887 Amer. Naturalist 21 151 The substance of the spindle, hitherto called achromatic, he [sc. Pfitzner] terms parachromatin.
1900 E. B. Wilson Cell (ed. 2) i. 41 The following classification of the nuclear substances, proposed by Schwarz in 1887, has been widely accepted, though open to criticism on various grounds. 1. Chromatin... 2. Linin... 3. Paralinin... 4. Pyrenin or Parachromatin. The inner mass of true nucleoli. 5. Amphipyrenin.
1960 R. A. Brink in Q. Rev. Biol. 35 133/2 The chromosome comprises two substances, orthochromatin and parachromatin, that pervade the genome, in intimate association.
1986 Internat. Jrnl. Cancer 38 361 Irregular parachromatin clearing (increase in the clarity of the clear spaces between chromatin threads, granules and clumps).
1995 Science 5 May 690/3 Brink's concept of parachromatin can be seen as a further elaboration on the Jacob-Monod hypothesis, one that recongnizes the dynamic, promoter-based regulatory complexity of active chromatin states.
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