oxaloaceticadj.
/ˌɒksələʊəˈsiːtɪk/, /ˌɒksələʊəˈsɛtɪk/, U.S. /ˈˌɑksəloʊəˈsɛdɪk/, /ˈˌɑksəloʊəˈsidɪk/, /ɑkˈˌsæloʊəˈsɛdɪk/, /ɑkˈˌsæloʊəˈsidɪk/ Chemistry.
Of or relating to oxaloacetic acid. oxaloacetic acid n. a dicarboxylic acid, HOOC·CO·CH2·COOH, which is an intermediate metabolite in the Krebs cycle and the C4 pathway of photosynthesis; (also) the enol form of this acid, HOOC·C(OH)=CH·COOH, which exists in cis and trans isomers.
ΚΠ
1896 Jrnl. Chem. Soc. 70 i. 599 Nef's ethylic ethoxyfumarate..when hydrolysed with hydrochloric acid, gives oxalacetic acid.
1924 J. B. Cohen Pract. Org. Chem. (ed. 3) 126 (heading) Oxaloacetic Ester, C2H5O.OC.CO.CH2.COOC2H5.
1937 Nature 18 Sept. 503/2 α-Ketoacids other than pyruvic, for example..oxaloacetic or phenylpyruvic acid, may equally serve as acceptors for the amino group of glutamic acid.
1968 R. Passmore & J. S. Robson Compan. Med. Stud. I. ix. 14/2 Acetyl-CoA reacts with oxaloacetic acid to produce citric acid.
1972 Arch. Biochem. & Biophysics 153 226/1 Oxalacetic acid..functions as a key substrate in metabolism as the keto form; however, the pure compound crystallizes as the cis enol of hydroxymaleic acid.
2000 Proc. National Acad. Sci. U.S.A. 97 12503/2 The intermediates in the cycle include relatively complicated molecules such as citric acid and oxaloacetic acid.
This entry has been updated (OED Third Edition, March 2005; most recently modified version published online March 2022).
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adj.1896