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单词 orlistat
释义

orlistatn.

Brit. /ˈɔːlᵻstat/, U.S. /ˈɔrləˌstæt/
Origin: Formed within English, by compounding. Etymons: an element of unknown origin, English, -listat , lipstatin n..
Etymology: < or-, of unknown origin + -listat, alteration of lipstatin n., from which the drug is manufactured.
Pharmacology.
A synthetic drug used in treating obesity which is an inhibitor of gastric and pancreatic lipase activity, reducing the proportion of dietary fat that is digested sufficiently to be absorbed; tetrahydrolipstatin, C29H53NO5.A proprietary name for this drug is Xenical.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > medicines used to affect nutrition > [noun] > anti-fat preparations
extenuative1818
anti-fat1882
starch blocker1981
orlistat1992
1992 Atlanta Jrnl. & Constit. 28 Dec. d3 Orlistat is expected to increase weight loss by 1 to 2 pounds per month.
1996 Jrnl. Clin. Pharmacol. 36 152 When beta-carotene was given during orlistat treatment, its absorption was reduced by approximately one-third.
2000 Daily Tel. 4 Jan. 14/4 Orlistat: helps stop up to 30 per cent of fat in the diet from being absorbed. Available in Britain for the clinically obese.
This is a new entry (OED Third Edition, September 2004; most recently modified version published online March 2022).
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n.1992
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