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单词 osteomalacia
释义

osteomalacian.

Brit. /ˌɒstɪəʊməˈleɪʃ(ɪ)ə/, U.S. /ˈˌɑstioʊməˈleɪʃ(i)ə/
Forms: 1700s– osteomalacia, 1800s osteomalakia.
Origin: A borrowing from Latin. Etymon: Latin osteomalacia.
Etymology: < post-classical Latin osteomalacia (1788 or earlier) < osteo- osteo- comb. form + ancient Greek μαλακία softness (see malacia n.). Compare French ostéomalacie (1814; also as ostéomalaxie, dated 1808 in Robert Dict. alphabétique et analogique (1986)).
Medicine.
Softening of the bones; spec. that due to inadequate mineralization, resulting from abnormal vitamin D, calcium, or phosphate metabolism. Formerly called malacosteon, mollities ossium.
ΘΚΠ
the world > health and disease > ill health > a disease > diseases of tissue > disorders of bones > [noun] > softening
osteomalacia1790
malacosteon1801
1790 Med. Commentaries 5 19 He [sc. Dr. Ekman] employs the generic name of Osteomalacia, as none of the others in use sufficiently distinguish this disease from other affections of the solids.
1825 W. Cumin in Edinb. Med. & Surg. Jrnl. 23 19 Osteo-malakia. I must crave indulgence for the adoption of this term, to which I have been induced by the existing deficiency of a generic word capable of denoting both rickets and mollities ossium.
1834 S. Cooper Good's Study Med. (ed. 4) IV. 249 (note) The genus softening of bones, he [sc. Dr. Cumin] proposes to call Osteo-malakia, and he divides it into two species.
1845 G. E. Day tr. J. F. Simon Animal Chem. II. 406 An analysis..of the bones of a man..who died from osteomalacia.
1873 Jrnl. Anthropol. Inst. 2 148 As to osteomalacia, I must not omit to cite the astonishing examples of skulls deformed by it.
1920 Glasgow Herald 19 Apr. 7 How tremendously the osteomalacia has increased during this last winter.
1949 H. W. C. Vines Green's Man. Pathol. (ed. 17) xvii. 462 The symptoms of osteomalacia or mollities ossium usually appear in the later months of pregnancy in a woman who has already had several children.
1971 Nature 5 Feb. 409/2 If rickets were widespread in Neanderthal man, osteomalacia would occur in the adult female pelvis, making parturition exceptionally difficult.
1988 Pract. Health Spring 39/2 If black and Asian people also have diets which are low in Vitamin D, they are particularly at risk of bone problems like childhood rickets or its adult equivalent, osteomalacia.

Derivatives

ˌosteomaˈlacial adj. [after German osteomalacisch (1865 in the passage translated in quot. 1876)] rare = osteomalacic adj.
ΘΚΠ
the world > health and disease > ill health > a disease > diseases of tissue > disorders of bones > [adjective] > softening
osteomalacial1876
osteomalacic1882
1876 J. Van Duyn & E. C. Seguin tr. E. L. Wagner Man. Gen. Pathol. 328 In osteomalacial bones [Ger. in osteomalacischen Knochen].
1907 C. von Noorden et al. Metabolism & Pract. Med. III. 1266 The chemical composition of osteomalacial bone..excludes the possibility of lactic acid.
This entry has been updated (OED Third Edition, September 2004; most recently modified version published online March 2022).
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n.1790
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