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单词 orotic
释义

oroticadj.

Brit. /ɒˈrɒtɪk/, /əˈrɒtɪk/, U.S. /ɔˈrɑdɪk/
Origin: A borrowing from Greek, combined with an English element; modelled on an Italian lexical item. Etymons: Greek ὀρός , -otic suffix.
Etymology: < ancient Greek ὀρός serum, whey ( < the same Indo-European base as classical Latin serum serum n.) + -otic suffix, after Italian orotico (G. Biscaro & E. Belloni 1905, in Ann. della Soc. Chim. di Milano 11 18). Compare orotate n.
Biochemistry.
orotic acid n. a crystalline acid which was discovered in milk and is an intermediate in pyrimidine biosynthesis; uracil-6-carboxylic acid, C5H4N2O4.
ΘΚΠ
the world > matter > chemistry > organic chemistry > acids obtained from animals > [noun] > in milk
galactic acid1788
lactic acid1789
paralactic acid1864
thebolactic acid1874
orotic acid1905
1905 Jrnl. Chem. Soc. 88 i. 672 The occurrence of small crystals of an organic compound in the mother liquor of lactose has led to the discovery of a new acid, orotic acid, which has been found to be a normal constituent of milk.
1944 Nature 26 Feb. 251/2 Four out of five of the strains of Group C streptococci of various types which were tested also needed uracil or orotic acid for optimal growth.
1965 T. L. V. Ulbricht Introd. Nucleic Acids vi. 70 Studies with bacterial mutants showed that orotic acid..was an effective precursor of both DNA and RNA pyrimidines.
1992 S. Rose Making of Memory 192 A research group in Magdeburg..claimed that large doses of a precursor of DNA, orotic acid, would improve memory in rats.
This entry has been updated (OED Third Edition, September 2004; most recently modified version published online March 2022).
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adj.1905
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