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单词 oligonucleotide
释义

oligonucleotiden.

Brit. /ˌɒlᵻɡə(ʊ)ˈnjuːklɪətʌɪd/, U.S. /ˈˌɑləɡoʊˈn(j)ukliəˌtaɪd/, /ˈˌoʊləɡoʊˈn(j)ukliəˌtaɪd/
Origin: Formed within English, by compounding; modelled on a German lexical item. Etymons: oligo- comb. form, nucleotide n.
Etymology: < oligo- comb. form + nucleotide n., after German oligo-nucleotid (F. G. Fischer et al. 1941, in Jrnl. f. prakt. Chem. 158 81).
Biochemistry.
A polynucleotide whose molecules are made up of a relatively small number of nucleotides.
ΚΠ
1942 Chem. Abstr. 36 785 From a study of dialysis coeffs., the oligonucleotide has a mol. wt. 3·5–5·3 times that of a mononucleotide.
1971 Nature 28 May 217/2 There were several oligonucleotides missing from the former RNA.
2001 Nature 3 May 15/1 By the end of this year there will no longer be a standard-scale synthesizer manufactured that is really suitable to make DNA or RNA oligonucleotides for research.
This entry has been updated (OED Third Edition, March 2004; most recently modified version published online March 2022).
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n.1942
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