单词 | okadaic |
释义 | okadaicadj. Biochemistry. okadaic acid n. a toxic compound, C44H68O13, which is a fatty acid derivative of a polycyclic polyether, occurs in some algae and protists (and in marine invertebrates that feed on them), and acts as an inhibitor of certain protein phosphatases. ΚΠ 1981 K. Tachibana et al. in Jrnl. Amer. Chem. Soc. 103 2469/1 A new polyether derivative of a C38 fatty acid, okadaic acid.., has been isolated independently from two sponges, Halichondria..okadai Kadota, a black sponge, commonly found along the Pacific coast of Japan, and H. melanodocia, a Caribbean sponge collected in the Florida Keys. 1990 Internat. Immunol. 2 1073 The addition of okadaic acid, which inhibits serine/threonine protein phosphatases, resulted in an increase in the stability of IL-2 mRNA. 1992 Chem. in Brit. (BNC) Feb. 99 The researchers say that DTX-2 is biogenetically related to two other agents, okadaic acid and DTX-1, which cause diarrhoea after eating toxin-contaminated shellfish. 2000 Sarsia 85 471 Okadaic acid..is produced by dinoflagellates such as Dinophysis acuminata and D. norvegica, which are common throughout the Baltic Sea. This is a new entry (OED Third Edition, March 2004; most recently modified version published online March 2022). < adj.1981 |
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