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synaptosome
synaptosome n.
Brit. 
/sᵻˈnaptə(ʊ)səʊm/
, /sᵻˈnaptə(ʊ)səʊm/U.S. /səˈnæptəˌsoʊm/
[-some comb. form] a presynaptic nerve ending which, when isolated, seals up to form an intact sac./səˈnæptəˌsoʊm/ΘΚΠ
the world > life > the body > nervous system > nerve > parts of nerves > [noun] > ending
nerve end1865
nerve ending1868
synaptosome1964
1964 V. P. Whittaker et al. in Biochem. Jrnl. XC. 293/1 The club-like presynaptic nerve endings resist disruption and are snapped or torn off from their attachments to form discrete particles (nerve-ending particles) in which all the main structural features of the nerve ending are preserved. For these particles we propose the name ‘synaptosomes’ in order to emphasize their relative homogeneity and their resemblance in physical properties to other subcellular organelles.
1973 Nature 9 Mar. 122/1 Isolation of intact synaptic nerve endings (synaptosomes) had made it possible to investigate transport across synaptic membranes.
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