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单词 nucleolar
释义

nucleolaradj.

Brit. /ˌnjuːklɪˈəʊlə/, /njuːˈklɪələ/, U.S. /ˌn(j)ukliˈoʊlər/, /ˌn(j)uˈkliələr/
Origin: Formed within English, by derivation. Etymons: nucleolus n., -ar suffix1.
Etymology: < nucleolus n. + -ar suffix1. N.E.D. (1907) gives only the pronunciation (niuklī·ŏlăɹ) /njuːˈkliːələ(r)/.
Biology.
Of the nature of or relating to a nucleolus.
ΘΚΠ
the world > life > biology > substance > cell > cell organelle or contents > [adjective] > having nucleus > nucleolus or paranucleus
nucleolated1843
nucleolar1849
intranucleolar1879
nucleolate1883
paranuclear1885
1849 C. H. Jones in Philos. Trans. (Royal Soc.) 139 121 They are..of a perfectly circular form, and contain, within a well-marked envelope, from three to five oval or subcircular vesicles, which have often a nucleolar corpuscle in their centre, and possess a high refractive power.
1861 R. T. Hulme tr. C. H. Moquin-Tandon Elements Med. Zool. ii. vii. 407 One or two very small corpuscles, or nucleolar [Fr. nucléaires] bodies, may sometimes be seen in the interior.
1890 Spectator 10 May From every ovum, before metamorphosis begins, one or more masses of nucleolar matter, the so-called ‘polar bodies’, are extruded.
1918 Bot. Gaz. 66 307 Not all of the entering nucleolus fuses with the receiving nucleolus, however, for coarse strands radiate out from the dense mass of nucleolar substance and appear to be adding to the reticulum of the nucleoplasm.
1946 Nature 27 July 121/1 In heat-killed grain there was no change in nucleolar size.
1987 S. M. Stahl et al. Cognitive Neurochem. xv. 277 Significant correlations between tangles and cell loss and nucleolar volume.

Compounds

nucleolar organizer n. (more fully nucleolar organizer region) a chromosomal region containing a cluster of ribosomal RNA genes, with which the nucleolus is associated.
ΚΠ
1934 B. McClintock in Zeitschr. f. Zellforschung u. Mikrosk. Anat. 21 322 The nucleolus develops through the activity of this body (refer[r]ed to as the nucleolar-organizing body or element).]
1941 Proc. Royal Soc. B. 130 144 The nucleolar organizer presumably lies in the secondary constriction seen in one of the A chromosomes at mitosis.
1975 Chromosoma 53 37 (title) Visualization of nucleolar organizer regions in mammalian chromosomes using silver staining.
1989 E. Lawrence Guide Mod. Biol. iii. 66 The rRNA genes are clustered in tandem repeats in regions in the chromosomes that come together to form the nucleolar organizer.
This entry has been updated (OED Third Edition, December 2003; most recently modified version published online March 2022).
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adj.1849
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