nikethamiden.
/nᵻˈkɛθəmʌɪd/, U.S. /nəˈkɛθəˌmaɪd/ Pharmacology.
A derivative of nicotinic acid used as a respiratory stimulant and analeptic; nicotinic acid diethylamide, (C5H4N)CON(CH2CH3)2.A proprietary name for this drug is Coramine.
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Coramine1925
Metrazol1928
nikethamide1940
pentylenetetrazol1949
Regaine1985
Rogaine1986
1940 Jrnl. Amer. Med. Assoc. 20 Jan. 249/2 Agreement was reached on the name ‘Nikethamide’..as the nonproprietary name for the substance introduced in medicine under the proprietary name of Coramine.
1951 A. Grollman Pharmacol. & Therapeutics viii. 168 Because of its analeptic action, nikethamide is used in acute respiratory depression of anesthesia, alcoholic intoxication, and overdosage with hypnotics.
1967 Canad. Med. Assoc. Jrnl. 97 48/2 Just as little appreciated will be the advocacy of analeptics (especially nikethamide) for neonatal asphyxia.
1985 M. F. Myles Textbk. Midwives (ed. 10) xiii. 207 Drugs such as nikethamide and digoxin should be at hand.
This entry has been updated (OED Third Edition, September 2003; most recently modified version published online March 2022).
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n.1940