nephrotoxinn.

Brit.

/ˌnɛfrə(ʊ)ˈtɒksɪn/, U.S.

/ˌnɛfroʊˈtɑks(ə)n/

Origin: Formed within English, by compounding; modelled on a French lexical item. Etymons: nephro- comb. form, toxin n.

Etymology: < nephro- comb. form + toxin n., after French néphrotoxine (E. Metchnikoff 1900, in Ann. de l'Inst. Pasteur 14 372). Compare nephrotoxic adj.

Medicine.

Originally: an antiserum produced by the injection of kidney tissue from one species into animals of another species, which causes kidney disease when reinjected into the donor species; (also) any antibody or autoantibody associated with kidney disease (now historical or disused). Later: any drug or other substance that is toxic to the kidneys.

ΘΚΠ

the world > life > biology > substance > process stimulators or inhibitors > toxin > [noun]

toxin1890

autointoxicant1891

autotoxin1894

leucocidin1894

cytotoxin1900

toxon1900

nephrotoxin1902

toxonoid1904

zootoxin1906

leucotoxin1908

phalloidin1909

vivotoxin1953

victorin1954

phalloin1959

bungarotoxin1963

pathotoxin1963

trichothecene1971

the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > types of

Russell body1892

precipitin1900

nephrotoxin1902

hepatotoxin1903

opsonin1903

autoantibody1905

concanavalin1917

isoantibody1919

reagin1925

immune globulin1934

macroglobulin1952

immunoglobulin1953

properdin1954

LATS1961

alloantibody1964

xenoantibody1974

monoclonal1980

abzyme1986

the world > physical sensation > use of drugs and poison > poison > [noun] > poison affecting other specific parts

hepatotoxin1903

nephrotoxin1961

genotoxin1979

1902 Jrnl. Chem. Soc. 86 ii. 443 Repeated injections into the rabbit..of kidney cells from the dog..provoke the appearance in the rabbit's blood of a substance, nephrotoxin, which is most harmful to the kidney cells of the dog.

1937 Jrnl. Exper. Med. 65 564 The nephrotoxic effect induced by anti-kidney serum is dependent upon a relatively organ specific antibody, nephrotoxin.

1961 A. G. White Clin. Disturbances of Renal Function v. 153 Among the nephrotoxins encountered most frequently in clinical practice is carbon tetrachloride.

1970 R. C. Muehrcke in F. W. Sunderman Lab. Diagnosis Kidney Dis. xxxvii. 444/1 Other nephrotoxins such as sulfonamides produce their adverse pathopharmacological effects through a hypersensitivity reaction.

1987 D. J. Weatherall et al. Oxf. Textbk. Med. (ed. 2) II. xviii. 68/2 The kidney, which filters and concentrates them [sc. nephrotoxic substances] and so exposes the renal tubules to high concentrations of the unbound nephrotoxins.

1999 Natural Toxins 7 167 Ochratoxin A is a carcinogen and nephrotoxin which can enter the food chain resulting in human exposure.

This entry has been updated (OED Third Edition, September 2003; most recently modified version published online March 2022).

单词	nephrotoxin
释义	nephrotoxinn. Brit. /ˌnɛfrə(ʊ)ˈtɒksɪn/, U.S. /ˌnɛfroʊˈtɑks(ə)n/ Origin: Formed within English, by compounding; modelled on a French lexical item. Etymons: nephro- comb. form, toxin n. Etymology: < nephro- comb. form + toxin n., after French néphrotoxine (E. Metchnikoff 1900, in Ann. de l'Inst. Pasteur 14 372). Compare nephrotoxic adj. Medicine. Originally: an antiserum produced by the injection of kidney tissue from one species into animals of another species, which causes kidney disease when reinjected into the donor species; (also) any antibody or autoantibody associated with kidney disease (now historical or disused). Later: any drug or other substance that is toxic to the kidneys. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > toxin > [noun] toxin1890 autointoxicant1891 autotoxin1894 leucocidin1894 cytotoxin1900 toxon1900 nephrotoxin1902 toxonoid1904 zootoxin1906 leucotoxin1908 phalloidin1909 vivotoxin1953 victorin1954 phalloin1959 bungarotoxin1963 pathotoxin1963 trichothecene1971 the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > types of Russell body1892 precipitin1900 nephrotoxin1902 hepatotoxin1903 opsonin1903 autoantibody1905 concanavalin1917 isoantibody1919 reagin1925 immune globulin1934 macroglobulin1952 immunoglobulin1953 properdin1954 LATS1961 alloantibody1964 xenoantibody1974 monoclonal1980 abzyme1986 the world > physical sensation > use of drugs and poison > poison > [noun] > poison affecting other specific parts hepatotoxin1903 nephrotoxin1961 genotoxin1979 1902 Jrnl. Chem. Soc. 86 ii. 443 Repeated injections into the rabbit..of kidney cells from the dog..provoke the appearance in the rabbit's blood of a substance, nephrotoxin, which is most harmful to the kidney cells of the dog. 1937 Jrnl. Exper. Med. 65 564 The nephrotoxic effect induced by anti-kidney serum is dependent upon a relatively organ specific antibody, nephrotoxin. 1961 A. G. White Clin. Disturbances of Renal Function v. 153 Among the nephrotoxins encountered most frequently in clinical practice is carbon tetrachloride. 1970 R. C. Muehrcke in F. W. Sunderman Lab. Diagnosis Kidney Dis. xxxvii. 444/1 Other nephrotoxins such as sulfonamides produce their adverse pathopharmacological effects through a hypersensitivity reaction. 1987 D. J. Weatherall et al. Oxf. Textbk. Med. (ed. 2) II. xviii. 68/2 The kidney, which filters and concentrates them [sc. nephrotoxic substances] and so exposes the renal tubules to high concentrations of the unbound nephrotoxins. 1999 Natural Toxins 7 167 Ochratoxin A is a carcinogen and nephrotoxin which can enter the food chain resulting in human exposure. This entry has been updated (OED Third Edition, September 2003; most recently modified version published online March 2022). < n.1902
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