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单词 niclosamide
释义

niclosamiden.

Brit. /nᵻˈkləʊsəmʌɪd/, U.S. /nɪˈkloʊsəˌmaɪd/
Origin: Formed within English, by compounding. Etymons: nitro- comb. form, chloro- comb. form2, salicyl n., amide n.
Etymology: < ni- (in nitro- comb. form) + -clo- (apparently representing chloro- comb. form2) + -sa- (probably representing salicyl n.) + amide n., elements in the chemical name.
Pharmacology.
An anthelmintic drug used to treat tapeworm infestations in humans and other mammals and also as a molluscicide; 2′,5-dichloro-4′-nitrosalicylanilide, C13H8Cl2N2O4.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > remedies for parasitic infections > [noun] > vermifuge or anthelminthic
scolecobrotic1661
anthelmintic1684
helminthagogue1704
vermifuge1718
taenifuge1844
vermicide1849
taenicide1857
oxyuricide1864
oxyurifuge1881
ficin1930
niclosamide1962
praziquantel1975
1962 Lancet 13 Oct. 791/2 The British Pharmacopoeia Commission has issued the following new supplementary list of approved names... Niclosamide.
1977 Drugs 13 124 Therapy for Cestodes is achieved most effectively with niclosamide.
1985 Ann. Internal Med. 102 550/1 Shown to be effective against Hymenolepis diminuta, the rat tapeworm, a cestude that occasionally infects humans..Niclosamide is also used in veterinary practices and as a molluscicide.
1996 Parasitol. Today 12 156/2 Schistosoma mansoni larvae are immobilized and killed within minutes of exposure to niclosamide ethanolamine salt at a concentration of 0.3 mg/l.
This is a new entry (OED Third Edition, September 2003; most recently modified version published online March 2022).
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n.1962
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