| 单词 | nick translation |
| 释义 | > as lemmasnick translation nick translation n. Biochemistry a process used esp. to insert labelled nucleotides into a strand of DNA, in which a DNA polymerase adds new nucleotides to the strand on one side of a nick whilst removing nucleotides from the strand on the other side, thus effectively replacing a sequence of nucleotides and translating the nick some distance along the strand. ΚΠ 1976 Chromosoma 54 16 The technique..includes the in vitro enzymatic synthesis of 3H-labelled DNA by DNA polymerase I from single strand breaks introduced by deoxyribonuclease I; a method first employed by Kelly et al. (1970) and commonly known as ‘nick-translation’ of DNA. 1993 Ann. Human Genetics 57 10 The probes were biotin labelled by nick translation. < as lemmas |
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