nalbuphinen.

Brit.

/ˈnalbjᵿfiːn/, U.S.

/ˈnælbjuˌfin/

Origin: A variant or alteration of another lexical item. Etymon: nalorphine n.

Etymology: Alteration of nalorphine n., with substitution of -bu- (in butyl n.) for -or-.

Pharmacology.

A synthetic opioid antagonist which is very similar to morphine in chemical structure and is given by injection (usually in the form of its hydrochloride) as an analgesic; (−)-(5R,6S,14S)-9a-cyclobutylmethyl-4,5-epoxymorphinan-3,6,14-triol, C₂₁H₂₇NO₄.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [noun] > other analgesics

Hoffmann's anodyne1747

acetylsalicylic acid1873

acetophenetidin1888

exalgin1889

pyramidon1898

aspirin1899

phenazone1899

Veganin1926

Trilene1935

Demerol1940

pethidine1942

Tridione1944

amidone1946

meperidine1947

methadone1947

Physeptone1947

Butazolidin1951

phenylbutazone1952

opioid1955

Panadol1955

propoxyphene1955

Tylenol1956

acetaminophen1957

paracetamol1957

Distalgesic1958

oxycodone1958

Sernyl1958

morphinomimetic1959

phencyclidine1959

levorphanol1960

mefenamic acid1962

pentazocine1964

Talwin1965

ibuprofen1967

nalbuphine1969

naproxen1971

phy1971

Nurofen1982

1969 WHO Chron. 23 194 Nalbuphine.

1970 Jrnl. Med. 1 74 Nalbuphine..is a potentially useful analgesic because of low toxicity, potent analgesic activity and moderate narcotic antagonist activity in animals.

1987 Brit. Med. Jrnl. 27 June 1685/2 Meptazinol for renal colic and nalbuphine for myocardial infarcts are in the British National Formulary and are adequate substitutes.

1998 Jrnl. Accident & Emergency Med. 15 99 There may be further scope for extending the indications for nalbuphine use by ambulance personnel.

This entry has been updated (OED Third Edition, June 2003; most recently modified version published online March 2022).

单词	nalbuphine
释义	nalbuphinen. Brit. /ˈnalbjᵿfiːn/, U.S. /ˈnælbjuˌfin/ Origin: A variant or alteration of another lexical item. Etymon: nalorphine n. Etymology: Alteration of nalorphine n., with substitution of -bu- (in butyl n.) for -or-. Pharmacology. A synthetic opioid antagonist which is very similar to morphine in chemical structure and is given by injection (usually in the form of its hydrochloride) as an analgesic; (−)-(5R,6S,14S)-9a-cyclobutylmethyl-4,5-epoxymorphinan-3,6,14-triol, C₂₁H₂₇NO₄. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [noun] > other analgesics Hoffmann's anodyne1747 acetylsalicylic acid1873 acetophenetidin1888 exalgin1889 pyramidon1898 aspirin1899 phenazone1899 Veganin1926 Trilene1935 Demerol1940 pethidine1942 Tridione1944 amidone1946 meperidine1947 methadone1947 Physeptone1947 Butazolidin1951 phenylbutazone1952 opioid1955 Panadol1955 propoxyphene1955 Tylenol1956 acetaminophen1957 paracetamol1957 Distalgesic1958 oxycodone1958 Sernyl1958 morphinomimetic1959 phencyclidine1959 levorphanol1960 mefenamic acid1962 pentazocine1964 Talwin1965 ibuprofen1967 nalbuphine1969 naproxen1971 phy1971 Nurofen1982 1969 WHO Chron. 23 194 Nalbuphine. 1970 Jrnl. Med. 1 74 Nalbuphine..is a potentially useful analgesic because of low toxicity, potent analgesic activity and moderate narcotic antagonist activity in animals. 1987 Brit. Med. Jrnl. 27 June 1685/2 Meptazinol for renal colic and nalbuphine for myocardial infarcts are in the British National Formulary and are adequate substitutes. 1998 Jrnl. Accident & Emergency Med. 15 99 There may be further scope for extending the indications for nalbuphine use by ambulance personnel. This entry has been updated (OED Third Edition, June 2003; most recently modified version published online March 2022). < n.1969
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