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单词 mosaicism
释义

mosaicismn.

Brit. /mə(ʊ)ˈzeɪɪsɪz(ə)m/, U.S. /moʊˈzeɪɪˌsɪz(ə)m/
Origin: Formed within English, by derivation. Etymons: mosaic n., -ism suffix.
Etymology: < mosaic n. + -ism suffix.
Genetics.
The condition of being (a) mosaic (mosaic n. 3b, mosaic adj.1 4).
ΘΚΠ
the world > life > biology > biological processes > genetic activity > heredity or hereditary descent > [noun] > combination of different genetic types
mosaicism1920
1920 Proc. Royal Soc. 1919–20 B. 91 187 Intermediate plants of composite or mosaic nature are not very uncommon, and the mosaicism may be of varying extent.
1932 Genetics 17 39 The facts secured from the different breeding tests demonstrate that the mosaicism is due to an unstable translocation.
1947 Nature 11 Jan. 66/2 Chemical treatment of female embryos [of Drosophila melanogaster] leads to high frequency of mosaicism.
1963 Lancet 13 May 1028/2 The term mosaicism, in cytogenetic usage, describes a condition in which a substantial minority of cells differ from the majority in their chromosomal content.
1971 Nature 11 June 388/2 We have recently had the opportunity to study the rare association of mixed gonadal dysgenesis in a female child and X/XY/XYY mosaicism in karyotypes from blood and fibroblast cultures.
1993 Sci. Amer. Apr. 12/1 In calico cats the resulting mosaicism is visible because each of their X chromosomes carries a different pigment gene.
2000 Jrnl. Med. Genetics 37 132 This is the first description of germline mosaicism shown by molecular genetic analysis in an autosomal dominant disorder.
This entry has been updated (OED Third Edition, December 2002; most recently modified version published online March 2022).
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n.1920
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