单词 | mitomycin c |
释义 | > as lemmasmitomycin C Any of a group of closely related antibiotics produced by the soil bacterium Streptomyces caespitosus; spec. (in full mitomycin C) the principal member of this group, which inhibits DNA synthesis by cross-linking the two chains of duplex DNA molecules and is used medically as an antineoplastic agent. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > antibiotics > [noun] > other antibiotics pyocyanase1900 fumigatin1938 M and B1938 gramicidin1940 tyrocidine1940 tyrothricin1940 clavacin1942 fumigacin1942 streptothricin1942 aspergillic acid1943 aspergillin1943 clavatin1943 helvolic acid1943 streptomycin1944 subtilin1944 bacitracin1945 viridin1945 javanicin1946 nisin1947 nitrofurazone1947 polymyxin1947 aureomycin1948 chloramphenicol1949 clitocybin1949 neomycin1949 Terramycin1950 viomycin1950 cephalosporin1951 fumagillin1951 nigericin1951 achromycin1952 carbomycin1952 erythromycin1952 nystatin1952 oxytetracycline1952 tetracycline1952 chlortetracycline1953 nitrofurantoin1953 oligomycin1953 puromycin1953 bacteriocin1954 albomycin1955 spiramycin1955 valinomycin1955 amphotericin B1956 mitomycin1956 novobiocin1956 oleandomycin1956 paromomycin1956 vancomycin1956 kanamycin1957 macrolide1957 ristocetin1957 streptovaricin1957 ethionamide1959 rifamycin1959 strep1959 mithramycin1960 fucidin1961 virginiamycin1961 cephalothin1962 fusidic acid1962 nonactin1962 trimethoprim1962 daunomycin1963 lincomycin1963 anthracycline1964 cephaloridine1964 spectinomycin1964 doxycycline1966 rifampicin1966 minocycline1967 rifampin1968 Adriamycin1969 daunorubicin1969 ribostamycin1970 doxorubicin1971 tobramycin1971 milbemycin1975 fluoroquinolone1984 1956 T. Hata et al. in Jrnl. Antibiotics (Tokyo) A. 9 141 (heading) Mitomycin, a new antibiotic from Streptomyces. 1956 T. Hata et al. in Jrnl. Antibiotics (Tokyo) A. 9 145 Mitomycins have a high antibacterial activity against gram positive and gram negative bacteria. 1958 Antibiotics & Chemotherapy 8 240 S[treptomyces] caespitosus, which produces mainly mitomycin A and B in some cultural conditions, produces mitomycin C exclusively under other conditions. 1968 Echols & Joyner in H. Fraenkel-Conrat Molecular Basis Virol. vi. 557 The treatments which produce induction of wild-type prophages are rather diverse (e.g., UV irradiation, growth in mitomycin C, thymine deprivation of a thymine requiring bacterium). 1978 Neuroradiology 16 434 We have been using superselective angiographic techniques to administer the antitumor drug mitomycin C directly into the feeding arteries of the tumor. 1991 Lancet 14 Sept. 694/2 Inactivation of infected cells was achieved by mitomycin C to block DNA synthesis, before fixation with paraformaldehyde. 2000 New Scientist 4 Mar. 82/2 (advt.) The project involves the development of a novel free-radical cyclisation approach to medically-important mitomycins. < as lemmas |
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