minihelixn.

Brit.

/ˌmɪnɪˈhiːlɪks/, U.S.

/ˌmɪniˈhilɪks/

Inflections: Plural minihelices.

Origin: Formed within English, by compounding. Etymons: mini- comb. form, helix n.

Etymology: < mini- comb. form + helix n.

Molecular Biology.

A short helical region of a larger nucleic acid molecule, esp. a tRNA; a synthetic analogue of such a region. Originally also: a very short sequence of complementary nucleotides (now rare).

ΚΠ

1978 Nature 10 Aug. 609/1 Acridines and ethidium are frameshift mutagens which intercalate into DNA and RNA, and into minihelices made of complementary dinucleotides.

1982 Science 26 Nov. 873/3 Cech points out that the 15-nucleotide fragment can fold back on itself to form a marginally stable five base-pair mini-helix.

1989 Nature 2 Feb. 478/2 The resulting hairpin minihelix..was synthesized using the template-primer system..and comprises twelve base pairs with a seven-nucleotide loop.

2000 Biochemistry 39 6546 Changing A36 to G in the minihelix resulted in a 260-fold reduction in k(cat) compared to minihelix(Phe) and a 13-fold increase in K(m).

This is a new entry (OED Third Edition, March 2002; most recently modified version published online March 2022).

单词	minihelix
释义	minihelixn. Brit. /ˌmɪnɪˈhiːlɪks/, U.S. /ˌmɪniˈhilɪks/ Inflections: Plural minihelices. Origin: Formed within English, by compounding. Etymons: mini- comb. form, helix n. Etymology: < mini- comb. form + helix n. Molecular Biology. A short helical region of a larger nucleic acid molecule, esp. a tRNA; a synthetic analogue of such a region. Originally also: a very short sequence of complementary nucleotides (now rare). ΚΠ 1978 Nature 10 Aug. 609/1 Acridines and ethidium are frameshift mutagens which intercalate into DNA and RNA, and into minihelices made of complementary dinucleotides. 1982 Science 26 Nov. 873/3 Cech points out that the 15-nucleotide fragment can fold back on itself to form a marginally stable five base-pair mini-helix. 1989 Nature 2 Feb. 478/2 The resulting hairpin minihelix..was synthesized using the template-primer system..and comprises twelve base pairs with a seven-nucleotide loop. 2000 Biochemistry 39 6546 Changing A36 to G in the minihelix resulted in a 260-fold reduction in k(cat) compared to minihelix(Phe) and a 13-fold increase in K(m). This is a new entry (OED Third Edition, March 2002; most recently modified version published online March 2022). < n.1978
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