Mitsudan.

Brit.

/mɪˈtsuːdə/, U.S.

/məˈtsudə/

Origin: From a proper name. Etymon: proper name Mitsuda.

Etymology: < the name of Kensuke Mitsuda (1876–1964), Japanese leprologist, who described a lepromin test around 1919. Compare Japanese Mitsuda hannō, Mitsuda shi hannō.

Medicine.

1. attributive and (now rare) in the genitive. Used with reference to a type of lepromin testing developed by Mitsuda; (now) (spec., esp. in Mitsuda reaction) designating the delayed type of response to lepromin, consisting of nodular infiltration of the skin developing between one and four weeks, and considered to be a measure of cell-mediated immunity.

ΚΠ

1933 Internat. Jrnl. Leprosy 1 36 I have determined the relationship between Mitsuda's reaction and the condition of leprosy.

1933 Internat. Jrnl. Leprosy 1 36 Reactions one month after injections of (v) Mitsuda's vaccine, negative.

1938 Internat. Jrnl. Leprosy 6 296 The leprolin (Mitsuda) test in the hands of leprosy workers in different parts of the world has given fairly consistent results along certain lines.

1984 M. J. Taussig Processes in Pathol. & Microbiol. (ed. 2) iv. 603 The Mitsuda reaction is an allergic granuloma stimulated by the presence of persistent intact (dead) organisms.

2000 Jrnl. Infectious Dis. 181 302 The Mitsuda test..has a high prognostic value for susceptibility or resistance to the lepromatous form of leprosy.

2. In compounds with the sense ‘in regard to the Mitsuda reaction‘, as Mitsuda-negative, Mitsuda-positive; also Mitsuda positivity.

ΚΠ

1941 Leprosy Rev. 12 7 An ordinary (Mitsuda-positive) neural case had become lepromatous.

1975 Jrnl. Clin. Microbiol. 1 279 The donors were healthy but were tuberculin and lepromin (Mitsuda) positive.

1988 Q. N. Myrvik & R. S. Weiser Fund. Med. Bacteriol. & Mycol. (ed. 2) xxvii. 403 Leprologists have generally held the view that uninfected Mitsuda-positive adults seldom, if ever, develop multibacillary disease upon becoming infected.

1990 Leprosy Rev. 61 347 A poor correlation between Mitsuda and Fernandez positivity is not explained.

2000 Internat. Jrnl. Leprosy & Other Mycobacterial Dis. 68 18 The histopathologic responses to both antigens were found to be similar, whether the animal was Mitsuda-negative (lepromatous) or Mitsuda-positive (tuberculoid).

This is a new entry (OED Third Edition, June 2002; most recently modified version published online March 2022).

单词	mitsuda
释义	Mitsudan. Brit. /mɪˈtsuːdə/, U.S. /məˈtsudə/ Origin: From a proper name. Etymon: proper name Mitsuda. Etymology: < the name of Kensuke Mitsuda (1876–1964), Japanese leprologist, who described a lepromin test around 1919. Compare Japanese Mitsuda hannō, Mitsuda shi hannō. Medicine. 1. attributive and (now rare) in the genitive. Used with reference to a type of lepromin testing developed by Mitsuda; (now) (spec., esp. in Mitsuda reaction) designating the delayed type of response to lepromin, consisting of nodular infiltration of the skin developing between one and four weeks, and considered to be a measure of cell-mediated immunity. ΚΠ 1933 Internat. Jrnl. Leprosy 1 36 I have determined the relationship between Mitsuda's reaction and the condition of leprosy. 1933 Internat. Jrnl. Leprosy 1 36 Reactions one month after injections of (v) Mitsuda's vaccine, negative. 1938 Internat. Jrnl. Leprosy 6 296 The leprolin (Mitsuda) test in the hands of leprosy workers in different parts of the world has given fairly consistent results along certain lines. 1984 M. J. Taussig Processes in Pathol. & Microbiol. (ed. 2) iv. 603 The Mitsuda reaction is an allergic granuloma stimulated by the presence of persistent intact (dead) organisms. 2000 Jrnl. Infectious Dis. 181 302 The Mitsuda test..has a high prognostic value for susceptibility or resistance to the lepromatous form of leprosy. 2. In compounds with the sense ‘in regard to the Mitsuda reaction‘, as Mitsuda-negative, Mitsuda-positive; also Mitsuda positivity. ΚΠ 1941 Leprosy Rev. 12 7 An ordinary (Mitsuda-positive) neural case had become lepromatous. 1975 Jrnl. Clin. Microbiol. 1 279 The donors were healthy but were tuberculin and lepromin (Mitsuda) positive. 1988 Q. N. Myrvik & R. S. Weiser Fund. Med. Bacteriol. & Mycol. (ed. 2) xxvii. 403 Leprologists have generally held the view that uninfected Mitsuda-positive adults seldom, if ever, develop multibacillary disease upon becoming infected. 1990 Leprosy Rev. 61 347 A poor correlation between Mitsuda and Fernandez positivity is not explained. 2000 Internat. Jrnl. Leprosy & Other Mycobacterial Dis. 68 18 The histopathologic responses to both antigens were found to be similar, whether the animal was Mitsuda-negative (lepromatous) or Mitsuda-positive (tuberculoid). This is a new entry (OED Third Edition, June 2002; most recently modified version published online March 2022). < n.1933
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