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单词 methaemoglobinaemia
释义

methaemoglobinaemiamethemoglobinemian.

Brit. /ˌmɛthiːməˌɡləʊbɪˈniːmɪə/, /ˌmɛθiːməˌɡləʊbɪˈniːmɪə/, U.S. /ˌmɛthiməˌɡloʊbəˈnimiə/
Forms: 1800s– methaemoglobinaemia, 1800s– methemoglobinemia (chiefly U.S.).
Origin: Formed within English, by derivation. Etymons: methaemoglobin n., -aemia suffix.
Etymology: < methaemoglobin n. + -aemia suffix.
Medicine.
The presence of an abnormally high concentration of methaemoglobin in the blood; any clinical condition (acquired or inherited) characterized by this.
ΚΠ
1888 Med. News 53 240 The author, in two cases, observed cyanosis, depending upon methemoglobinemia.
1945 Science 23 Nov. 521/1 Methemoglobinemia may result from the administration of certain drugs or from the absorption of toxic materials used in industry.
1964 M. Hynes Med. Bacteriol. (ed. 8) x. 133 Every chemotherapeutic agent and antibiotic has its peculiar side-effects, such as methæmoglobinæmia from sulphonamides.
1976 Proc. National Acad. Sci. U.S.A. 73 1581/2 This substitution allows the β-hemes to become oxidized in erythrocytes and the patient suffers from methemoglobinemia.
1990 Which? Aug. 432/1 High levels of nitrates can increase the risk of methaemoglobinaemia (‘blue baby syndrome’), a very rare blood condition.
2000 Blood 95 3250 Recessive congenital methemoglobinemia due to nicotinamide adenine dinucleotide-cytochrome b5 reductase deficiency is classified into 2 clinical types: type 1 (erythrocyte type) and type 2 (generalized type).
This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022).
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