membranoproliferativeadj.
/ˌmɛmbrənəʊprəˈlɪf(ə)rətɪv/, U.S. /ˌmɛmbrəˌnoʊprəˈlɪfərədɪv/ Pathology.
Designating a form of glomerulonephritis characterized by thickening of glomerular basement membranes and mesangial proliferation. Cf. membranous glomerulonephritis n. at membranous adj. Compounds.
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1968 Lancet 13 July 78/1 In 15 of these patients biopsy specimens showed a characteristic renal morphology–proliferative glomerulonephritis with capillary wall thickening (‘membranoproliferative’ glomerulonephritis).
1971 Medicine 50 322/1 In biopsies from 14 patients the changes were consistent with the histologic criteria for membranoproliferative glomerulonephritis (MPGN).
1984 J. R. Tighe & D. R. Davies Pathol. (ed. 4) xviii. 177 Gradual impairment of function..is usually much slower in pure mesangial proliferation than with the membranoproliferative form.
2000 Jrnl. Amer. Vet. Med. Assoc. 216 46 Membranoproliferative glomerulonephropathy was diagnosed in 5 of 7 adult Beagles from the same litter.
This is a new entry (OED Third Edition, June 2001; most recently modified version published online March 2022).
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adj.1968