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megacolon
megacolon n. 
/ˈmɛɡəˌkəʊlɒn/,
Brit. /ˈmɛɡəˌkəʊlən/
, /ˈmɛɡəˌkəʊlən//ˈmɛɡəˌkəʊlɒn/U.S. /ˈmɛɡəˌkoʊlən/
[ < mega- comb. form + colon n.1; compare French mégacôlon (1901)] Medicine gross dilatation of the colon; a colon in this condition./ˈmɛɡəˌkoʊlən/ΘΚΠ
the world > health and disease > ill health > a disease > disorders of internal organs > disorders of bowels or intestines > [noun] > other intestinal disorders
cholera1601
cœliac1661
cœliac passion or flux1662
bota1722
mucocele1897
Hirschsprung's disease1900
paraproctitis1900
peptic ulcer1900
megacolon1906
outpouching1909
typhlatony1913
polyposis1914
argentaffinoma1934
irritable bowel syndrome1943
Meckel's diverticulum1946
Meckel's diverticulitis1954
1897 G. M. Gould & W. L. Pyle Anomalies & Curiosities Med. vi. 288 Mya reports two cases of congenital dilatation and hypertrophy of the colon (megacolon congenito).]
1906 W. A. N. Dorland Illustr. Med. Dict. (ed. 4) 419/2 Megacolon.
1908 Practitioner Sept. 459 True congenital idiopathic megacolon, or Hirschsprung's disease.
1949 Lancet 1 Jan. 10/2 A considerable proportion of cases of megacolon (not being Hirschsprung's disease) remain in the residual ‘idiopathic’ group.
1989 Nature 2 Feb. 464/2 This overexpression correlated with changes in the normal developmental program of the gut, resulting in an inherited abnormal phenotype known as megacolon.
1997 Gut 41 253/1 More proximal colonic specimens from 18 patients, 16 of whom had a megacolon.
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as lemmas