mecillinamn.

Brit.

/mɛˈsɪlɪnam/, U.S.

/məˈsɪlɪnəm/

Origin: Formed within English, by compounding. Etymons: methyl n., penicillin n., amino- comb. form.

Etymology: < me- (in methyl n.) + -cillin (in penicillin n.) + am- (in amino- comb. form).

Pharmacology.

A semi-synthetic antibiotic, C₁₅H₂₃N₃O₃S, related to penicillin, which is administered intravenously or intramuscularly, esp. in the treatment of infection by Gram-negative enteric bacteria.The U.S. Approved Name (1989) is amdinocillin.

ΚΠ

1975 Chemotherapy 21 146 Mecillinam (FL 1060) is a new β-lactam antibiotic synthesized in our laboratories and first described by Lund and Tybring.

1977 Lancet 29 Oct. (outside back cover) The introduction of Selexid (mecillinam), the first amidino-penicillin, represents a new chapter in the history of antibiotics.

1981 Sci. Amer. June 68/3 A temperature-sensitive mutant of E. coli has been isolated that shows increased resistance to two beta-lactum antibiotics (mecillinam and thienamycin) and a decrease in the affinity of its PBP2 for these substances.

1999 Injury 30 341 The most common pathogen was Escherichia coli, sensitive for mecillinam in 98% of the cases.

This is a new entry (OED Third Edition, June 2001; most recently modified version published online March 2022).

单词	mecillinam
释义	mecillinamn. Brit. /mɛˈsɪlɪnam/, U.S. /məˈsɪlɪnəm/ Origin: Formed within English, by compounding. Etymons: methyl n., penicillin n., amino- comb. form. Etymology: < me- (in methyl n.) + -cillin (in penicillin n.) + am- (in amino- comb. form). Pharmacology. A semi-synthetic antibiotic, C₁₅H₂₃N₃O₃S, related to penicillin, which is administered intravenously or intramuscularly, esp. in the treatment of infection by Gram-negative enteric bacteria.The U.S. Approved Name (1989) is amdinocillin. ΚΠ 1975 Chemotherapy 21 146 Mecillinam (FL 1060) is a new β-lactam antibiotic synthesized in our laboratories and first described by Lund and Tybring. 1977 Lancet 29 Oct. (outside back cover) The introduction of Selexid (mecillinam), the first amidino-penicillin, represents a new chapter in the history of antibiotics. 1981 Sci. Amer. June 68/3 A temperature-sensitive mutant of E. coli has been isolated that shows increased resistance to two beta-lactum antibiotics (mecillinam and thienamycin) and a decrease in the affinity of its PBP2 for these substances. 1999 Injury 30 341 The most common pathogen was Escherichia coli, sensitive for mecillinam in 98% of the cases. This is a new entry (OED Third Edition, June 2001; most recently modified version published online March 2022). < n.1975
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