单词 | autoimmune |
释义 | autoimmuneadj. Medicine. 1. Originally: designating serum and red blood cells derived from the same patient, esp. one with an infectious disease. Also: exhibiting naturally occurring immunity to a pathogen or foreign substance (cf. autoimmunity n. 1). rare. Now disused. ΘΚΠ the world > life > biology > biological processes > immunogenesis > [adjective] > immune response hetero-immune1903 autoimmune1908 heterogenetic1918 heterophile1920 heterophilic1929 isoimmune1938 immunocompetent1963 1908 L. S. Dudgeon in Proc. Royal Soc. B. 80 543 The first example was a case of acute pneumonia..in which a mixture containing 75 per cent. of auto-immune serum produced complete hæmolysis on auto-immune red cells. 1916 Trop. Vet. Bull. 4 114 Loss of agglutinability towards serum immune against the original micrococcus, increase of non-specific agglutinability, but specific agglutinability towards an auto-immune serum persists. 1921 E. H. Robinson Smiling Pass 72 Almost anyone except a mountaineer would have had a bad case of septicemia by now, but they're auto-immune against most diseases. 2. Of or relating to autoimmunity (autoimmunity n. 2); characterized by, resulting from, or exhibiting autoimmunity. Esp. in autoimmune disease, autoimmune disorder. ΘΚΠ the world > life > biology > biological processes > immunogenesis > [adjective] > immune response > auto-immunity autoaggressive1940 autoimmune1952 1952 Amer. Jrnl. Med. 13 24/2 The thrombocytopenia in certain cases of sedormid sensitivity is due to an auto-immune mechanism resulting in platelet destruction. 1987 R. A. Thompson & L. S. Thompson Egoshell ii. C-x. 241 Evidence also suggests that multiple sclerosis may be the result of an autoimmune reaction. In this instance autoantibodies are created that attack the myelin, the fatty sheath surrounding the central nervous system. 1995 Denver Post 16 Jan. e2/6 More than 2 million Americans have lupus, an autoimmune disease that..essentially results in the body becoming ‘allergic’ to itself. 2002 Ladies' Home Jrnl. Nov. 186/3 An autoimmune disorder, juvenile rheumatoid arthritis (JRA) causes inflammation, redness and soreness in joints. This entry has been updated (OED Third Edition, June 2011; most recently modified version published online December 2021). < adj.1908 |
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