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单词 ligase
释义

ligasen.

/ˈlɪɡeɪz//ˈlɪɡeɪs/
Etymology: < Latin ligāre to bind + -ase suffix.
Biochemistry.
(See quot. 1961.)
ΚΠ
1961 Rep. Comm. Enzymes Internat. Union Biochem. vi. 39 Enzymes catalysing the linking together of two molecules, coupled with the breaking of a pyrophosphate link in ATP, etc., will be known as ligases (pronounced with a short ‘i’ in English). These enzymes have hitherto been known as synthetases... A new systematic name was necessary.
1965 Canad. Jrnl. Biochem. 43 1605 Succinate: CoA ligase (ADP)..catalyzes the formation of succinyl CoA.
1972 Sci. Amer. Jan. 31/1 The most unusual of them is an enzyme that is named polynucleotide ligase, which repairs breaks in DNA molecules.
This entry has not yet been fully updated (first published 1976; most recently modified version published online September 2018).
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n.1961
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