Liebermann–Burchardn.
/ˌliːbəmanˈbʊəkɑːt/ Biochemistry.
Liebermann–Burchard reaction, the reaction of unsaturated sterols with acetic anhydride and sulphuric acid in chloroform, which produces various coloured solutions; used esp. as a test for cholesterol, when a blue-green colour is produced; so Liebermann–Burchard test.
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the world > matter > chemistry > organic chemistry > organic chemical tests > [noun] > others
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the world > matter > chemistry > organic chemistry > chemical processes or reactions > processes or reactions attributed to chemists > [noun] > others
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1904 W. R. Orndorff tr. E. L. Salkowski Lab. Man. Physiol. & Pathol. Chem. ix. 92 (heading) Liebermann–Burchard reaction.
1915 T. L. Stedman Pract. Med. Dict. (ed. 3) 509/2 Liebermann–Burchard test.
1934 Jrnl. Biol. Chem. 106 746 The very weak color produced by digitonin with the modified Liebermann–Burchard reaction.
1956 E. V. Truter Wool Wax vii. 185 At present, the only technique for quantitatively determining alcohols of the isocholesterol group is based upon the spectrophotometric measurement of the colour developed in the Liebermann–Burchardt test.
1968 Indian Jrnl. Med. Res. 56 1776 A method for the estimation of total cholesterol in whole blood, serum or plasma, based on the Liebermann–Burchard reaction is presented.
This entry has not yet been fully updated (first published 1976; most recently modified version published online June 2018).
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