autosomal dominantn.adj.

Brit.

/ˌɔːtəˈsəʊml ˈdɒmᵻnənt/, U.S.

/ˌɔdəˈsoʊm(ə)l ˈdɑmənənt/,

/ˌɑdəˈsoʊm(ə)l ˈdɑmənənt/

Origin: Formed within English, by compounding. Etymons: autosomal adj., dominant n.

Etymology: < autosomal adj. + dominant n. Compare autosomal recessive n. and slightly earlier autosomal recessive adj.

Genetics.

A. n.

A dominant gene located on an autosome; a trait whose inheritance is determined by such a gene.

ΘΚΠ

the world > life > biology > biological processes > genetic activity > genetic components > [noun] > gene > types of gene

sex determinant1902

sex determiner1909

inhibitor1911

multiple factor1912

modifier1915

autosomal dominant1919

autosomal recessive1919

scute1923

gene1925

suppressor1928

rate gene1932

dominigene1938

buffer1939

polygene1941

switch gene1942

mutator1943

oligogene1943

sickle cell gene1946

supergene1949

ob1950

obese1950

regulator1960

regulator gene1960

regulatory gene1960

enhancer1967

oncogene1969

virogene1969

hedgehog1980

1919 T. H. Morgan Physical Basis Heredity xx. 273 In both the factor is an autosomal dominant; it affects the hairs, certain bristles, and the second, fourth and fifth veins of the wings, and has a recessive lethal effect.

1939 Nature 23 Sept. 557/1 Rex is an autosomal dominant to normal.

1968 New Eng. Jrnl. Med. 7 Mar. 564/1 This disorder is probably inherited as a single autosomal dominant.

2002 R. Frankham et al. Introd. Conservation Genetics vii. 162 For mutations that are equally deleterious, autosomal recessives have the highest frequencies and autosomal dominants the lowest.

B. adj.

Of a gene or trait: that is an autosomal dominant. Also: of, relating to, or characteristic of such a gene or trait; determined by such a gene.

ΘΚΠ

the world > life > biology > biological processes > genetic activity > heredity or hereditary descent > [adjective] > other

bequeathed1619

inheriting1622

propagablea1707

pure-bred1810

prepotent1859

pedigree1861

amphigonous1876

dominant1900

codominant1908

autosomal dominant1922

1922 Genetics 7 356 Minute is an autosomal dominant mutant.

1955 Ann. Human Genetics 19 312 The nail patella syndrome or hereditary onchyo-osteodysplasia is controlled by a regular autosomal dominant gene.

1994 Guardian 17 June 6/5 About 50,000 people in Britain suffer from autosomal dominant polycystic kidney disease, which can be inherited from either parent and affects on average half their children.

2005 J. E. Richards & R. S. Hawley Human Genome (ed. 2) xix. 187 Huntington disease..is autosomal dominant, which means that it only takes one defective copy of the gene to initiate the disease.

This is a new entry (OED Third Edition, June 2011; most recently modified version published online December 2021).

单词	autosomal dominant
释义	autosomal dominantn.adj. Brit. /ˌɔːtəˈsəʊml ˈdɒmᵻnənt/, U.S. /ˌɔdəˈsoʊm(ə)l ˈdɑmənənt/, /ˌɑdəˈsoʊm(ə)l ˈdɑmənənt/ Origin: Formed within English, by compounding. Etymons: autosomal adj., dominant n. Etymology: < autosomal adj. + dominant n. Compare autosomal recessive n. and slightly earlier autosomal recessive adj. Genetics. A. n. A dominant gene located on an autosome; a trait whose inheritance is determined by such a gene. ΘΚΠ the world > life > biology > biological processes > genetic activity > genetic components > [noun] > gene > types of gene sex determinant1902 sex determiner1909 inhibitor1911 multiple factor1912 modifier1915 autosomal dominant1919 autosomal recessive1919 scute1923 gene1925 suppressor1928 rate gene1932 dominigene1938 buffer1939 polygene1941 switch gene1942 mutator1943 oligogene1943 sickle cell gene1946 supergene1949 ob1950 obese1950 regulator1960 regulator gene1960 regulatory gene1960 enhancer1967 oncogene1969 virogene1969 hedgehog1980 1919 T. H. Morgan Physical Basis Heredity xx. 273 In both the factor is an autosomal dominant; it affects the hairs, certain bristles, and the second, fourth and fifth veins of the wings, and has a recessive lethal effect. 1939 Nature 23 Sept. 557/1 Rex is an autosomal dominant to normal. 1968 New Eng. Jrnl. Med. 7 Mar. 564/1 This disorder is probably inherited as a single autosomal dominant. 2002 R. Frankham et al. Introd. Conservation Genetics vii. 162 For mutations that are equally deleterious, autosomal recessives have the highest frequencies and autosomal dominants the lowest. B. adj. Of a gene or trait: that is an autosomal dominant. Also: of, relating to, or characteristic of such a gene or trait; determined by such a gene. ΘΚΠ the world > life > biology > biological processes > genetic activity > heredity or hereditary descent > [adjective] > other bequeathed1619 inheriting1622 propagablea1707 pure-bred1810 prepotent1859 pedigree1861 amphigonous1876 dominant1900 codominant1908 autosomal dominant1922 1922 Genetics 7 356 Minute is an autosomal dominant mutant. 1955 Ann. Human Genetics 19 312 The nail patella syndrome or hereditary onchyo-osteodysplasia is controlled by a regular autosomal dominant gene. 1994 Guardian 17 June 6/5 About 50,000 people in Britain suffer from autosomal dominant polycystic kidney disease, which can be inherited from either parent and affects on average half their children. 2005 J. E. Richards & R. S. Hawley Human Genome (ed. 2) xix. 187 Huntington disease..is autosomal dominant, which means that it only takes one defective copy of the gene to initiate the disease. This is a new entry (OED Third Edition, June 2011; most recently modified version published online December 2021). < n.adj.1919
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