| 单词 | rb gene |
| 释义 | > as lemmasRb gene = retinoblastoma n.. Also: (more fully Rb gene) the retinoblastoma gene, which suppresses the formation of retinoblastomas and other tumours; (more fully Rb protein) the protein that this gene encodes. ΘΚΠ the world > health and disease > ill health > a disease > disorders of eye > [noun] > disorders of retina retinitis1821 retinitis pigmentosa1859 retinal detachment1860 detached retina1863 choroido-retinitis1869 neuroretinitis1878 chorioretinitis1880 pseudoglioma1884 macular degeneration1918 retinoblastoma1924 pseudofovea1925 retinopathy1930 RP1975 Rb1976 1976 Med. & Pediatric Oncol. 2 379 Sporadic bilateral Rb associated with a long-arm deletion of a D-group chromosome has been reported in 8 children. 1986 S. H. Friend et al. in Nature 16 Oct. 644/1 This malignant tumour, which arises in the eyes of children, can be explained as the result of two distinct genetic changes, each causing loss of function of one of the two homologous copies at a single genetic locus, Rb.., assigned to the q14 band of human chromosome 13. 1987 Nature 15 Oct. 642/2 To identify the RB protein, we selected several human cell lines known to have either normal or altered RB gene expression. 2003 Jrnl. Urol. 170 1987/2 Deletions of genes encoding rb..and p53..are common in human bladder cancers. 2005 Genes & Developm. 18 1681/1 The RB gene was the first known tumor suppressor gene identified. < as lemmas |
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