arsphenaminen.

Brit.

/ɑːsˈfɛnəmiːn/,

/ɑːsˈfɛnəmɪn/, U.S.

/ˌɑrsˈfɛnəmən/,

/ˌɑrsˈfɛnəˌmin/

Origin: Formed within English, by compounding. Etymons: arsenic n., phen- comb. form, amine n.

Etymology: < ars- (in arsenic n.) + phen- comb. form + amine n., components of the molecular structure.

Pharmacology. Now historical.

A toxic organic arsenic compound formerly used to treat syphilis, yaws, and other treponemal diseases. Also: any of a group of structurally similar arsenical drugs including this and neoarsphenamine. Cf. Salvarsan n.The arsphenamine molecule was thought to consist of two aminophenol rings linked by two arsenic atoms, C₁₂H₁₂O₂N₂As₂. Later studies have indicated three or five rings with correspondingly more arsenic atoms.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for venereal disease or syphilis > for syphilis and yaws

Salvarsan1910

arsphenamine1917

Mapharsen1932

Mapharside1936

1917 Drug & Chem. Markets 5 Dec. 13/1 Hereafter this important drug will be manufactured and sold under the name of arsphenamine.

1935 Lancet 13 July 74/2 A sensitivity to the arsphenamines may develop gradually.

1950 G. M. Findlay Recent Adv. Chemotherapy (ed. 3) I. i. 8 The first of these arsenobenzene derivatives, arsphenamine..contained both amino- and hydroxy-groups in the benzene nucleus.

1977 S. Sontag Illness as Metaphor viii. 65 In 1910, Paul Ehrlich introduced an arsenic derivative, arsphenamine (Salvarsan), which was called ‘the magic bullet’.

2015 T. Hart Health City vi. 170 Children had received intramuscular injections of arsphenamine and mercury.

This entry has been updated (OED Third Edition, September 2018; most recently modified version published online December 2021).

单词	arsphenamine
释义	arsphenaminen. Brit. /ɑːsˈfɛnəmiːn/, /ɑːsˈfɛnəmɪn/, U.S. /ˌɑrsˈfɛnəmən/, /ˌɑrsˈfɛnəˌmin/ Origin: Formed within English, by compounding. Etymons: arsenic n., phen- comb. form, amine n. Etymology: < ars- (in arsenic n.) + phen- comb. form + amine n., components of the molecular structure. Pharmacology. Now historical. A toxic organic arsenic compound formerly used to treat syphilis, yaws, and other treponemal diseases. Also: any of a group of structurally similar arsenical drugs including this and neoarsphenamine. Cf. Salvarsan n.The arsphenamine molecule was thought to consist of two aminophenol rings linked by two arsenic atoms, C₁₂H₁₂O₂N₂As₂. Later studies have indicated three or five rings with correspondingly more arsenic atoms. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for venereal disease or syphilis > for syphilis and yaws Salvarsan1910 arsphenamine1917 Mapharsen1932 Mapharside1936 1917 Drug & Chem. Markets 5 Dec. 13/1 Hereafter this important drug will be manufactured and sold under the name of arsphenamine. 1935 Lancet 13 July 74/2 A sensitivity to the arsphenamines may develop gradually. 1950 G. M. Findlay Recent Adv. Chemotherapy (ed. 3) I. i. 8 The first of these arsenobenzene derivatives, arsphenamine..contained both amino- and hydroxy-groups in the benzene nucleus. 1977 S. Sontag Illness as Metaphor viii. 65 In 1910, Paul Ehrlich introduced an arsenic derivative, arsphenamine (Salvarsan), which was called ‘the magic bullet’. 2015 T. Hart Health City vi. 170 Children had received intramuscular injections of arsphenamine and mercury. This entry has been updated (OED Third Edition, September 2018; most recently modified version published online December 2021). < n.1917
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