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单词 homocystine
释义

homocystinen.

/hɒməʊˈsɪstiːn/
Etymology: < homodynamous adj. (b) at homo- comb. form 1 + cystine n.
Chemistry.
An amino-acid (—S·CH2·CH2·CH(NH2)·COOH)2, which is the oxidized form of homocysteine.
ΚΠ
1932 Jrnl. Biol. Chem. 99 136 We have drawn the conclusion that the compound is bis-(γ-amino-γ-carboxy~propyl) disulphide, the next higher symmetrical homologue of cystine. Because of this relationship we wish to suggest the name of homocystine for the compound.
1962 Biochem. & Biophysical Res. Communications IX. 493 (heading) The identification of homocystine in the urine.

Derivatives

ˌhomocystiˈnuria n. [-uria comb. form] a rare condition, caused by a hereditary enzyme deficiency, in which homocystine is present in the urine.
ΘΚΠ
the world > health and disease > ill health > a disease > disorders of internal organs > urinary disorders > [noun] > other substances in urine
pyuria1772
albuminuria1838
azoturia1838
oxaluria1844
hippuria1847
mellituria1848
cystinuria1853
phosphuria1854
phosphoruria1858
chyluria1860
glycosuria1860
bacilluria1881
acetonuria1883
urobilinuria1887
alkaptonuria1888
bacteriuria1889
melanuria1890
peptonuria1890
xanthinuria1890
indicanuria1897
postural albuminuria1897
acholuria1900
pentosuria1902
proteinuria1911
ketonuria1913
porphyrinuria1916
hypercalcuria1930
porphobilinogenuria1949
natriuresis1957
maple syrup disease1959
saluresis1959
homocystinuria1962
1962 Carson & Neill in Arch. Dis. Childhood XXXVII. 512/2 The following abnormalities were discovered... A so far undescribed abnormality in cystine metabolism, homocystinuria.
1969 New Scientist 3 July 10/1 Prevention of postnatal brain damage by dietary treatment has been reported in a number of other inborn errors of metabolism. Examples include galactosaemia, tyrosinosis, maple syrup urine disease and possibly homocystinuria.
This entry has not yet been fully updated (first published 1976; most recently modified version published online September 2018).
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n.1932
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