histocompatibilityn.

Brit.

/ˌhɪstəʊkəmpatᵻˈbɪlᵻti/, U.S.

/ˌhɪstoʊkəmpædəˈbɪlᵻdi/

Origin: Formed within English, by compounding. Etymons: histo- comb. form, compatibility n.

Etymology: < histo- comb. form + compatibility n. Compare later histocompatible adj.

The condition that permits transplantation of tissue or organs between individuals, resulting from sufficient similarity of certain cell-surface antigens to prevent destruction of the transplant by the host's immune system. Frequently attributive. Cf. compatibility n. 2b.

ΘΚΠ

the world > life > biology > laboratory analysis > material > [noun] > conditions of material

compatibility1918

histocompatibility1948

1948 G. D. Snell in Jrnl. Genetics 49 87 Genes of the type postulated in the genetic theory of tumour transplantation will be here referred to as histocompatibility genes. The prefix ‘histo’ is used because the same genes which determine susceptibility or resistance to tumour transplants probably also determine susceptibility or resistance to tissue transplants in general.

1969 N. A. Mitchison et al. Organ Transplantation Today 26 The genetic system controlling histocompatibility is not too complicated to defy analysis.

1991 Univ. Maryland Graduate School Catal. 1991–3 48/3 The course will concentrate on such topics as..histocompatibility; immunogenetics; transplantation and tumor immunology.

2009 R. Powers Generosity 207 He has read how people choose their mates on smell and some sixth sense, a pheromone whiff off histocompatibility complexes other than their own, but recognized.

Compounds

histocompatibility antigen n. any of the cell-surface antigens involved in the determination of histocompatibility; esp. any antigen of the major histocompatibility complex (the HLA system in humans and H-2 system in mice) (see major histocompatibility complex n. at major adj. and n.¹ Compounds).

ΚΠ

1948 Nature 2 Oct. 514/1 Tumour-transplantability depends on a number of genes, some of which determine the production of specific antigens, identified as the ‘histo-compatibility’ antigens.

1977 Ann. Internal Med. 86 699/1 The tissue histocompatibility antigen B27 (HLA B27) is a disease marker for ankylosing spondylitis.

2006 B. A. Pierce Genetics (ed. 2) xxi. 627/1 The variation in histocompatibility antigens provides each of us with a unique identity for our own cells, which allows our immune systems to distinguish self from nonself.

This entry has been updated (OED Third Edition, March 2012; most recently modified version published online March 2022).

单词	histocompatibility
释义	histocompatibilityn. Brit. /ˌhɪstəʊkəmpatᵻˈbɪlᵻti/, U.S. /ˌhɪstoʊkəmpædəˈbɪlᵻdi/ Origin: Formed within English, by compounding. Etymons: histo- comb. form, compatibility n. Etymology: < histo- comb. form + compatibility n. Compare later histocompatible adj. The condition that permits transplantation of tissue or organs between individuals, resulting from sufficient similarity of certain cell-surface antigens to prevent destruction of the transplant by the host's immune system. Frequently attributive. Cf. compatibility n. 2b. ΘΚΠ the world > life > biology > laboratory analysis > material > [noun] > conditions of material compatibility1918 histocompatibility1948 1948 G. D. Snell in Jrnl. Genetics 49 87 Genes of the type postulated in the genetic theory of tumour transplantation will be here referred to as histocompatibility genes. The prefix ‘histo’ is used because the same genes which determine susceptibility or resistance to tumour transplants probably also determine susceptibility or resistance to tissue transplants in general. 1969 N. A. Mitchison et al. Organ Transplantation Today 26 The genetic system controlling histocompatibility is not too complicated to defy analysis. 1991 Univ. Maryland Graduate School Catal. 1991–3 48/3 The course will concentrate on such topics as..histocompatibility; immunogenetics; transplantation and tumor immunology. 2009 R. Powers Generosity 207 He has read how people choose their mates on smell and some sixth sense, a pheromone whiff off histocompatibility complexes other than their own, but recognized. Compounds histocompatibility antigen n. any of the cell-surface antigens involved in the determination of histocompatibility; esp. any antigen of the major histocompatibility complex (the HLA system in humans and H-2 system in mice) (see major histocompatibility complex n. at major adj. and n.¹ Compounds). ΚΠ 1948 Nature 2 Oct. 514/1 Tumour-transplantability depends on a number of genes, some of which determine the production of specific antigens, identified as the ‘histo-compatibility’ antigens. 1977 Ann. Internal Med. 86 699/1 The tissue histocompatibility antigen B27 (HLA B27) is a disease marker for ankylosing spondylitis. 2006 B. A. Pierce Genetics (ed. 2) xxi. 627/1 The variation in histocompatibility antigens provides each of us with a unique identity for our own cells, which allows our immune systems to distinguish self from nonself. This entry has been updated (OED Third Edition, March 2012; most recently modified version published online March 2022). < n.1948
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