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hexamethonium
hexamethonium n.
Brit. 
/ˌhɛksəmɛˈθəʊnɪəm/
, /ˌhɛksəmɛˈθəʊnɪəm/U.S. /ˌhɛksəmɛˈθoʊniəm/
a quaternary ammonium ion, [(CH3)3N(CH2)6N(CH3)3]++; (also) any of the salts of this ion, some of which have been used as ganglionic blocking drugs in the treatment of severe hypertension./ˌhɛksəmɛˈθoʊniəm/ΘΚΠ
the world > matter > chemistry > organic chemistry > organic ions > [noun]
carboxylate1884
sulphonium1894
oxonium1899
hexamethonium1949
lipoate1954
tropylium1954
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders
Neo-Synephrine1934
Priscol1938
phenylephrine1947
hexamethonium1949
Priscoline1949
methonium1950
hydralazine1952
phentolamine1953
methyldopa1954
pentolinium1954
mecamylamine1955
hydrochlorothiazide1958
pempidine1958
guanethidine1959
hydroflumethiazide1959
thiazide1959
pheniprazine1960
pargyline1961
vasodepressor1961
alpha blocker1965
clonidine1969
prazosin1970
timolol1973
1949 Jrnl. Pharmacy & Pharmacol. 1 603 An antidote exists for decamethonium iodide in hexamethonium iodide..and..this substance has been suggested for use in hypertension and vascular diseases.
1964 S. Duke-Elder Parsons' Dis. Eye (ed. 14) xxi. 300 The operation is most conveniently done under basal anæsthesia, and the systemic administration of sympatholytic drugs such as hexamethonium may be of value in relieving congestion by lowering the general blood pressure.
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