英语词汇“haploinsufficiency”的英英意思、用法、释义、翻译、读音、例句、短语、词组-英语词典

> as lemmas

haploinsufficiency

haploinsufficiency n.

Brit.

/ˌhapləʊɪnsəˈfɪʃnsi/

U.S.

/ˌhæploʊˌɪnsəˈfɪʃənsi/

the condition characterized by the presence of only a single functioning copy of a gene which requires two functional copies to produce its normal effect.

ΚΠ

1981 Developmental Biol. 85 301/2 Clones bearing only one dose of M(2)c⁺ and therefore mutant for that M due to the haploinsufficiency of the M loci.

1995 Proc. National Acad. Sci. U.S.A. 92 8568/3 The detected mutations appear to cause loss of function or haploinsufficiency.

2008 Nature 17 Jan. 252/2 It now seems that haploinsufficiency is a frequent genetic mechanism underlying human cancers.

extracted from haplo-comb. form

as lemmas

单词	haploinsufficiency
释义	> as lemmas haploinsufficiency haploinsufficiency n. Brit. /ˌhapləʊɪnsəˈfɪʃnsi/ , U.S. /ˌhæploʊˌɪnsəˈfɪʃənsi/ the condition characterized by the presence of only a single functioning copy of a gene which requires two functional copies to produce its normal effect. ΚΠ 1981 Developmental Biol. 85 301/2 Clones bearing only one dose of M(2)c⁺ and therefore mutant for that M due to the haploinsufficiency of the M loci. 1995 Proc. National Acad. Sci. U.S.A. 92 8568/3 The detected mutations appear to cause loss of function or haploinsufficiency. 2008 Nature 17 Jan. 252/2 It now seems that haploinsufficiency is a frequent genetic mechanism underlying human cancers. extracted from haplo-comb. form < as lemmas
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