guanosinen.

/ˈɡwɑːnəsiːn/

Forms: Formerly also guanosin.

Etymology: < German Guanosin (Levene & Jacobs 1909, in Berichte der Deutsch. Chem. Ges. 42 2470), < guanine n., by insertion of -ose suffix².

Chemistry.

A nucleoside, C₁₀H₁₃N₅O₅, which yields guanine and ribose on hydrolysis and is itself a hydrolysis product of ribonucleic acid.

ΚΠ

1909 Chem. Abstr. 3 2562 Guaninepentoside, C₁₀H₁₃O₅N₅.2H₂O, termed ‘guanosin’ by the authors.

1968 A. White et al. Princ. Biochem. (ed. 4) xlix. 1035 Guanosine is directly utilized for pteridine synthesis.

Draft additions September 2018

guanosine diphosphate n. a nucleotide that is both a precursor and breakdown product of guanosine triphosphate, and functions as a regulatory agent in metabolic processes; abbreviated GDP.Guanosine diphosphate has a chain of two phosphate groups. Chemical name: guanosine 5'-diphosphate.

ΚΠ

1954 Med. Times (N.Y.) Mar. 120 a/2 The University of Wisconsin cancer researchers recently announced discovery of a group of new building blocks for body cells..: guanosine monophosphate, abbreviated as GMP; guanosine diphosphate, GDP; guanosine triphosphate, GTP.

1988 N.Y. Times (Nexis) 23 Feb. c3/1 All [the mutations] are in positions to influence the crucial chemistry by which the protein normally functions—by cutting a molecule called guanosine triphosphate (GTP) into a closely related form, guanosine diphosphate (GDP).

2010 P. Connett et al. Case against Fluoride iv. xii. 119 Some biological switching devices..are controlled by substituting guanosine triphosphate for guanosine diphosphate.

guanosine monophosphate n. any phosphoric monoester or diester of guanosine; spec. guanosine 5'-phosphate; abbreviated GMP.Also called guanylic acid.cyclic guanosine monophosphate: see cyclic GMP n. at cyclic adj. Additions.

ΚΠ

1954 Cancer Res. 14 73/2 The acid-soluble components were..shown to include the cytidine-, uridine-, guanosine-, and adenosine-5'-mono-, di-, and triphosphates.

1971 Science 9 Apr. 163/1 Hypoxanthine could be replaced by other purines or purine derivatives, such as adenosine monophosphate, adenosine triphosphate, and guanosine monophosphate.

2009 M. Lieberman & A. D. Marks Marks' Basic Med. Biochem. (ed. 3) xli. 766 Adenosine monophosphate (AMP) and guanosine monophosphate (GMP) are each derived from IMP in two-step reaction pathways.

guanosine triphosphate n. a nucleotide that is a source of energy for various physiological processes including protein synthesis, and which also participates in various synthetic reactions requiring a phosphate residue; abbreviated GTP.Guanosine triphosphate has a chain of three phosphate groups, the hydrolysis of which releases energy. Chemical name: guanosine 5'-triphosphate.

ΚΠ

1954 Cancer Res. 14 73/2 The acid-soluble components were..shown to include the cytidine-, uridine-, guanosine-, and adenosine-5'-mono-, di-, and triphosphates.

1992 Sci. Amer. Sept. 54/1 Its members interact with a neighboring membrane protein that cleaves a high-energy phosphate bond from guanosine triphosphate.

2015 Free Press Jrnl. (India) (Nexis) 25 Mar. A precursor molecule (guanosine triphosphate or GTP) is converted into the second messenger cyclic guanosine monophosphate (cGMP).

This entry has not yet been fully updated (first published 1972; most recently modified version published online December 2020).

单词	guanosine
释义	guanosinen. /ˈɡwɑːnəsiːn/ Forms: Formerly also guanosin. Etymology: < German Guanosin (Levene & Jacobs 1909, in Berichte der Deutsch. Chem. Ges. 42 2470), < guanine n., by insertion of -ose suffix². Chemistry. A nucleoside, C₁₀H₁₃N₅O₅, which yields guanine and ribose on hydrolysis and is itself a hydrolysis product of ribonucleic acid. ΚΠ 1909 Chem. Abstr. 3 2562 Guaninepentoside, C₁₀H₁₃O₅N₅.2H₂O, termed ‘guanosin’ by the authors. 1968 A. White et al. Princ. Biochem. (ed. 4) xlix. 1035 Guanosine is directly utilized for pteridine synthesis. Draft additions September 2018 guanosine diphosphate n. a nucleotide that is both a precursor and breakdown product of guanosine triphosphate, and functions as a regulatory agent in metabolic processes; abbreviated GDP.Guanosine diphosphate has a chain of two phosphate groups. Chemical name: guanosine 5'-diphosphate. ΚΠ 1954 Med. Times (N.Y.) Mar. 120 a/2 The University of Wisconsin cancer researchers recently announced discovery of a group of new building blocks for body cells..: guanosine monophosphate, abbreviated as GMP; guanosine diphosphate, GDP; guanosine triphosphate, GTP. 1988 N.Y. Times (Nexis) 23 Feb. c3/1 All [the mutations] are in positions to influence the crucial chemistry by which the protein normally functions—by cutting a molecule called guanosine triphosphate (GTP) into a closely related form, guanosine diphosphate (GDP). 2010 P. Connett et al. Case against Fluoride iv. xii. 119 Some biological switching devices..are controlled by substituting guanosine triphosphate for guanosine diphosphate. guanosine monophosphate n. any phosphoric monoester or diester of guanosine; spec. guanosine 5'-phosphate; abbreviated GMP.Also called guanylic acid.cyclic guanosine monophosphate: see cyclic GMP n. at cyclic adj. Additions. ΚΠ 1954 Cancer Res. 14 73/2 The acid-soluble components were..shown to include the cytidine-, uridine-, guanosine-, and adenosine-5'-mono-, di-, and triphosphates. 1971 Science 9 Apr. 163/1 Hypoxanthine could be replaced by other purines or purine derivatives, such as adenosine monophosphate, adenosine triphosphate, and guanosine monophosphate. 2009 M. Lieberman & A. D. Marks Marks' Basic Med. Biochem. (ed. 3) xli. 766 Adenosine monophosphate (AMP) and guanosine monophosphate (GMP) are each derived from IMP in two-step reaction pathways. guanosine triphosphate n. a nucleotide that is a source of energy for various physiological processes including protein synthesis, and which also participates in various synthetic reactions requiring a phosphate residue; abbreviated GTP.Guanosine triphosphate has a chain of three phosphate groups, the hydrolysis of which releases energy. Chemical name: guanosine 5'-triphosphate. ΚΠ 1954 Cancer Res. 14 73/2 The acid-soluble components were..shown to include the cytidine-, uridine-, guanosine-, and adenosine-5'-mono-, di-, and triphosphates. 1992 Sci. Amer. Sept. 54/1 Its members interact with a neighboring membrane protein that cleaves a high-energy phosphate bond from guanosine triphosphate. 2015 Free Press Jrnl. (India) (Nexis) 25 Mar. A precursor molecule (guanosine triphosphate or GTP) is converted into the second messenger cyclic guanosine monophosphate (cGMP). This entry has not yet been fully updated (first published 1972; most recently modified version published online December 2020). < n.1909
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