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单词 frusemide
释义

frusemiden.

/ˈfruːsəmʌɪd/
Forms: Also (chiefly U.S.) furosemide, (in early use) fursemide.
Etymology: < fur- (in furyl n.) (subsequently rearranged as fru- ) + sem-, of unknown origin + -ide suffix.
Pharmacology.
A potent diuretic drug, C12H11ClN2O5S, used esp. in the treatment of oedema; 4-chloro-N-furfuryl-5-sulphamoylanthranilic acid.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > cleansing or expelling medicines > [noun] > diuretic > specific
Haarlem oil1885
Salyrgan1924
mersalyl1936
acetazolamide1954
chlorothiazide1957
thiazide1959
triamterene1962
ethacrynic acid1963
frusemide1963
1963 Jrnl. Amer. Med. Assoc. 18 May 576/2 (table) Nonproprietary name, fursemide.
1964 Jrnl. Amer. Med. Assoc. 20 July 227/1 Nonproprietary name, furosemide... Note: Fursemide was the former nonproprietary name for this compound.
1964 Lancet 21 Nov. 1085/2 Frusemide (‘Lasix’)..contains the same sulphamoylbenzene grouping as chlorothiazide and chlorthalidone... Nevertheless, preliminary data available when the drug was offered for clinical trial in Great Britain (under the name of furosemide) suggested that it differed in action from the thiazides.
1971 D. Lambert in C. Bonington Annapurna South Face App. G. 296 Singh found that in over 400 cases of mountain sickness in unacclimatized soldiers..considerable improvement resulted from administering frusemide, better known by its trade name Lasix.
1977 Lancet 23 Apr. 910/1 She..was given several drugs for her respiratory problem including aminophylline..,frusemide (furosemide), and nitroglycerine.
1989 J. A. B. Collier & J. M. Longmore Oxf. Handbk. Clin. Specialties (ed. 2) iii. 224 Treat heart failure in babies with nasogastric feeds, sitting upright, O2, frusemide eg 1mg/kg/24h IV and digoxin 10μg/kg/24h PO.
This entry has not yet been fully updated (first published 1993; most recently modified version published online December 2020).
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n.1963
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