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5-fluorouracil
fluorouracil n. 
/ˌflɔːrə(ʊ)ˈjʊərəsɪl/, /ˌflɔːrə(ʊ)ˈjɔːrəsɪl/, /ˌflɔroʊˈjʊrəˌsɪl/ (in full 5-fluorouracil) a fluorine-substituted derivative of uracil which inhibits DNA synthesis and is used as a chemotherapy drug in the treatment of cancer.
Brit. /ˌflʊərə(ʊ)ˈjʊərəsɪl/
, /ˌflʊərə(ʊ)ˈjʊərəsɪl//ˌflɔːrə(ʊ)ˈjʊərəsɪl//ˌflɔːrə(ʊ)ˈjɔːrəsɪl/U.S. /ˌflʊroʊˈjʊrəˌsɪl/
, /ˌflʊroʊˈjʊrəˌsɪl//ˌflɔroʊˈjʊrəˌsɪl/ΚΠ
1957 C. Heidelberger et al. Nature 30 Mar. 663/2 We have synthesized a number of hitherto unknown 5-fluoropyrimidines and their 2-thio derivatives. 5-Fluoro-uracil..and 5-fluoro-orotic acid..exert considerable anti-tumour activity.
1994 M. M. Sherry Confronting Cancer iii. 44 Two chemotherapy drugs, fluorouracil (5-FU) and levamizole, effectively reduced the recurrence rate of stage C colon cancer when administered following surgery.
2008 Daily Tel. 22 Apr. 1/4 The drug 5-fluorouracil..is used for tumours of the breast, ovary, colon, stomach, skin, pancreas and bladder.
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