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单词 digitoxin
释义

digitoxinn.

Brit. /ˌdɪdʒᵻˈtɒksɪn/, U.S. /ˌdɪdʒᵻˈtɑksən/
Forms: 1800s– digitoxin, 1800s– digitoxine.
Origin: A borrowing from German. Etymon: German Digitoxin.
Etymology: < German Digitoxin (O. Schmiedeberg 1874, in Arch. f. exper. Pathol. u. Pharmakol. 3 18) < Digi- (in Digitalis digitalis n.) + -toxin (in Pikrotoxin picrotoxin n.). Compare French digitoxine (1880 or earlier). Compare digoxin n.
Pharmacology.
A potent cardiac glycoside obtained from digitalis. Cf. digoxin n.Digitoxin is a polycyclic compound with a steroid nucleus and a trisaccharide sugar component.
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the world > matter > chemistry > organic chemistry > carbohydrates > sugars > [noun] > glycosides > named > others
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1875 Pharmaceut. Jrnl. & Trans. 20 Mar. 741/2 The author [sc. Schmiedeberg] has prepared a new, well-defined, crystallizable principle, Digitoxin, from the leaves of Digitalis purpurea.
1886 Lancet 8 May 909/1 M. Nativelle's digitaline, though amorphous and yellow, is, chemically speaking, identical with Merck's digitoxine.
1922 J. J. Sudborough Bernthsen's Text-bk. Org. Chem. (new ed.) xlii. 633 Digitonin, digitalin, and digitaleïn are three glucosides which, together with digitoxin (the most important constituent from a pharmacological point of view), are present in the digitalis of commerce.
1953 Cedar Rapids (Iowa) Gaz. 20 Dec. 6/3 Out of such studies may come understanding of how a drug like Digitoxin makes the heart a more efficient pump.
1999 Independent 14 May (Mag.) 54/3 Digitalis is no longer used in its original form, but the purified forms of digoxin and digitoxin are currently back in fashion because of their proven ability to keep heart-failure patients out of hospital.
This is a new entry (OED Third Edition, November 2010; most recently modified version published online March 2022).
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n.1875
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