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单词 agmatine
释义

agmatinen.

Brit. /ˈaɡmətiːn/, U.S. /ˈæɡməˌtin/, /ˈæɡməd(ə)n/
Forms: 1900s agmantine (irregular), 1900s– agmatin, 1900s– agmatine.
Origin: A borrowing from German. Etymon: German Agmatin.
Etymology: < German Agmatin (A. Kossel 1910, in Zeitschr. f. physiol. Chem. 66 257), probably < A- (in Amino- amino- comb. form) + g- (in Guanidin guanidine n.) + -ma- (in Ptomain ptomaine n.) + -in -ine suffix5, with insertion of -t- apparently for euphony.
Biochemistry.
An amine produced by the decarboxylation of arginine during the degradation of proteins.Systematic name: 4-aminobutylguanidine; H2N(CH2)4NHC(NH)NH2.
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the world > matter > chemistry > organic chemistry > amines > [noun] > named
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triethylamine1850
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nonylamine1866
octylamine1866
carbylamine1868
tetrylamine1868
hydroxylamine1871
hydramine1877
nitrosamine1878
guanamine1881
hexamethylenetetramine1888
morpholine1889
triethanolamine1897
tropane1898
agmatine1910
tyramine1910
histamine1912
spermidine1927
monoethanolamine1929
tryptamine1929
octopamine1948
norsynephrine1952
tilorone1970
1910 Independent 15 Dec. 1338/2 Kossel..has published the synthesis of agmatin, a base formed from arginin by splitting off CO2 by a reaction between cyanamid and tetramethylendiamin.
1930 J. B. S. Haldane Enzymes vi. 107 Agmatine is unaffected by mammalian or fungal arginase.
1972 Jrnl. Bacteriol. 109 44/1 In recent years evidence has accumulated that agmatine can replace arginine as an energy source for the growth of certain strains of S. faecalis.
1986 M. Kogut tr. H. G. Schlegel Gen. Microbiol. xiv. 434 The best known of these bases (formerly called ptomaines) are cadaverine, putrescine, and agmatine.
2007 Proc. National Acad. Sci. U.S.A. 104 9982/2 Agmatine was shown to stimulate nitrite formation as well as Ca2+ uptake in endothelial cells.
This entry has been updated (OED Third Edition, September 2012; most recently modified version published online December 2021).
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n.1910
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