the world > action or operation > difficulty > hindrance > types or manners of hindrance > hinder in specific manner [verb (transitive)] > by depriving of vigour or energy (2)
transitive. literal. Of a bird, etc.: To cease to ply vigorously, relax the efforts of (its wings) from fatigue. Of conditions, circumstances, etc…
transitive. to take it (also a lot, too much,etc.) out of (a person): to exhaust, fatigue (a person).