With defining word: that which is evil in some particular case or relation; the evil portion or element of anything. Also quasi-abstract as in to…

Something which causes difficulty or distress; a source of suffering.

That which causes distress; a trouble, a sorrow. Obsolete.

transferred. A thing or person that gives trouble; an occasion or cause of affliction or distress.

Suffering, grief, trouble; (also) a source or object of fear or worry. Cf. dreich, n. 1.