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单词 centrosome
释义

centrosomen.

Brit. /ˈsɛntrə(ʊ)səʊm/, U.S. /ˈsɛntrəˌsoʊm/
Inflections: Plural centrosomes, centrosomata.
Forms:

α. 1800s– centrosoma.

β. 1800s– centrosome.

Origin: Formed within English, by compounding. Etymons: centro- comb. form, -some comb. form.
Etymology: < centro- comb. form + -some comb. form.In sense 1 after German Centrosoma (also Centrosom; 1888 in this sense: T. Boveri, in Jenaische Zeitschr. Naturw. 22 752), itself after French corpuscule central (1887 in this sense: E. van Beneden & A. Neyt Nouvelles recherches sur la fécondation et la division mitosique chez l'Ascaride mégalocéphale 52). With use in sense 2 compare German Centrosoma (also Centrosom; 1895 in this sense: T. Boveri, in Verh. d. Physik.-Med. Ges. Würzburg 29 66; now Zentrosom).
Cell Biology.
1. The small structure or body located at the centre of the aster during mitosis, the parts of which were subsequently distinguished as centriole (see centriole n.), centrosome (see sense 2), and centrosphere (see centrosphere n. 2). Obsolete (historical in later use).
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the world > life > biology > biological processes > genetic activity > genetic components > [noun] > chromosome > centriole
centrosome1889
centriole1895
1889 P. Geddes & J. A. Thomson Evol. Sex xi. 146 Both Van Beneden and Boveri have recently agreed on the existence of two ‘central corpuscles’ (centrosomata) in the protoplasm.
1893 W. N. Parker & H. Rönnfeldt tr. A. Weismann Germ-plasm 25 The splitting is completed by the two halves being gradually drawn further apart towards the opposite poles of the nuclear spindle, until they finally approach the centre of attraction or centrosome.
1900 G. C. Bourne Introd. Compar. Anat. Anim. iii. 116 The centrosomata..divide very precociously during the telophase.
1912 E. A. Minchin Introd. Study Protozoa vi. 81 To the primary centrosome or centriole there may be added adventitious elements of protoplasmic or nuclear origin, thus forming a centrosomic complex.
1925 E. B. Wilson Cell (ed. 3) 1127 Centrosome, (1) originally, the central body lying at the astral center, and constituting an autonomous cell-organ; the division-center or dynamic center of the cell (Boveri, 1888).
2. An organelle, usually located near the nucleus of a cell, which is involved in the regulation of cell cycle progression and the organization of microtubules in the cell, esp. those which form the mitotic spindle. In animal cells the centrosome usually consist of two centrioles embedded in an amorphous mass of protein.
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the world > life > biology > substance > cell > cell organelle or contents > [noun] > other organelles or contents
raphide1831
body1839
raphid1863
mucigen1874
cell sap1875
globoid1875
raphis1879
pyrenoid1883
mucinogen1884
plastid1885
molluscum corpuscle1886
hyalosome1889
molluscum body1892
statolith1892
dictyosome1893
centrosome1895
Nissl body1898
Nissl granule1898
Nissl substance1899
archespore1901
blepharoplast1907
liposome1910
statocone1910
kinetosome1912
Golgi body1916
kinetoplast1925
lipochondrion1936
microsome1943
kappa1945
Pappenheimer body1947
microbody1954
lysosome1955
siderosome1957
ribosome1958
melanosome1961
cisterna1962
microtubule1962
plasmalemmasome1962
phagolysosome1963
informosome1964
monosome1964
mucocyst1965
peroxisome1965
rhoptry1967
spectrin1968
virosome1970
the world > life > biology > biological processes > genetic activity > genetic components > [noun] > chromosome > centrosome
centrosome1895
1895 Jrnl. Morphol. 11 468 The central mass of the sperm-aster, derived from the middle-piece, forms the centrosome..and at first contains no discernable centriole.
1925 E. B. Wilson Cell (ed. 3) 1127 Centrosome, (2)..in a more specific sense, the larger central body, composed of centroplasm, within which lies the much smaller centriole (Boveri, 1895, 1901).
1943 L. W. Sharp Fund. Cytol. 28 The aspect of the centrosome varies widely in cells of different kinds and especially in different stages of nuclear division.
1964 F. Brown & J. F. Danielli in G. H. Bourne Cytol. & Cell Physiol. (ed. 3) vi. 292 The second stage [of egg activation] follows engulfment of the spermatozoon and it is the centrosome which plays the active role and organizes the division apparatus.
2000 Nature 18 May 292/1 In most animal cells, a pair of centrioles resides in the centrosome—a macromolecular complex that organizes the microtubule system (part of the cell's internal skeleton).

Derivatives

ˌcentroˈsomal adj. of or relating to a centrosome (in either sense).
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1897 Proc. Acad. Sci. Calif.: Zool. 1 8 In this way the centrosomal spheres in the leucocytes are brought out strongly and chromatically.
1989 B. Alberts et al. Molecular Biol. Cell (ed. 2) xiii. 763 During interphase, the centrosomal material nucleates the growth of microtubules.
2008 Science 8 Feb. 695 Pericentrin, a centrosomal protein implicated in mitotic spindle anchoring and chromosome separation during cell division.
ˌcentroˈsomic adj. = centrosomal adj.
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the world > life > biology > substance > cell > cell organelle or contents > [adjective] > other organelles or contents
mucigenous1886
centrosomic1895
chromosomal1895
microsomal1897
lipochondrial1946
kinetosomal1949
microsomal1951
lysosomal1957
ribosomal1959
microtubular1963
peroxisomal1967
phagolysosomal1975
phagosomal1975
the world > life > biology > biological processes > genetic activity > genetic components > [adjective] > chromosome > centrosome
centrosomic1895
centriolar1911
1895 A. H. Buck Ref. Handbk. Med. Sci. IX. 402/2 As soon as cell division sets in..radiating lines are seen in the cytoplasm above and below the nucleus, these are called the centrosomic filaments, since they proceed from the two centrosomes.
1908 Q. Jrnl. Microsc. Sci. Mar. 253 I am unable to agree with Salvin-Moore and Breinl in regarding the kinetonucleus as of centrosomic nature.
2011 Internat. Jrnl. Oncol. 38 779/2 During prophase..and metaphase..PAR [= prostate androgen regulated (protein)] is localized in the centrosomic region and along the spindle fibers.
This entry has been updated (OED Third Edition, June 2016; most recently modified version published online December 2021).
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