dor·nase al·fa 
(dôrnās′ ălfə, -nāz′)
(dôrnās′ ălfə, -nāz′)n.
A genetically engineered enzyme used to hydrolyze the DNA in bronchial mucus, facilitating its expectoration, in the treatment of cystic fibrosis.
[(recombinant human) d(e)o(xy)r(ibo)n(ucle)ase (1) + alteration of ALPHA.]