释义 |
cryostat|ˈkraɪəʊstæt| [f. cryo- + -stat.] An apparatus for maintaining a very low temperature.
1913Chem. Abstr. VII. 2327 A Helium Cryostat. Ibid., Making use of the He cryostat O. [i.e. K. Onnes] has detd. the vapor pressure of liquid He. 1917Ibid. 2976 Cryostat for temperatures between 27°K and 55°K. 1946Nature 24 Aug. 272/1 The experiments can be made in an ordinary cryostat. 1969Brown & Bertke Textbk. Cytology iii. 19/1 Recently a refrigerated unit to cut frozen sections (cryostat) has become available. Hence cryoˈstatic a.; spec. cryostatic hypothesis (see quot.).
1950A. L. Washburn in Rev. Canadienne Géogr. IV. iii. 34 Progressive freezing from the surface downward to the permafrost table sets up a large hydrostatic pressure in the unfrozen material that is confined between these surfaces... Because of analogy with a hydrostatic press and because freezing is the initiating factor, the writer suggests that this concept be termed the cryostatic hypothesis.
▸ Biol. and Med. A microtome designed to be used at very low temperatures inside a refrigerated chamber. Also: a unit consisting of a cold chamber and the microtome inside it.
[1951Jrnl. Exper. Med. 93 175 Linderstrøm-Lang and Mogensen solved this problem by placing their microtome in an insulated box cooled with dry ice and provided with gloved armholes, windows and adequate lighting. Sections cut in such a cryostat from frozen tissue remain in a tight roll at the tip of the knife and cannot be unrolled.] 1971Lancet 25 Sept. 682 Fresh tissues were obtained every few days and snap-frozen at -70°C in isopentane, and sections 4–6 µ thick were cut with a cryostat. 1992S. Rose Making of Memory 248 The frozen brain is mounted in the laboratory equivalent of a tiny meat slicer, called a cryostat, and sliced sequentially into very thin sections. 2005Jrnl. Neurosci. Methods 144239/1 Another mounting method is to stick tissue sections to the glass slide directly from the knife of the microtome or cryostat. |