| 释义 |
pyruvic, a. Chem.|paɪˈruːvɪk|
[ad. mod.L. pyruvicus, in acidum pyruvicum pyruvic acid (J. J. Berzelius 1835, in Ann. der Physik u. Chem. XXXVI. 5), f. pyro- 3 a + L. uva grape + -ic.]
In pyruvic acid, C3H4O3 = CH3.CO.CO2H, also called pyroracemic acid, produced by the dry distillation of racemic or tartaric acid; a liquid smelling like acetic acid, and boiling at about 165° C. The acid occurs widely in living organisms as an intermediate in many metabolic processes, notably glycolysis. So pyruvic alcohol = acetyl carbinol, CH3.CO.CH2OH; pyruvic aldehyde = methyl glycoxal, CH3.CO.CHO; pyruvic kinase = pyruvate kinase; pyruvic oxidase, any enzyme or enzyme complex which catalyses the oxidation of pyruvic acid.
1838T. Thomson Chem. Org. Bodies 65 Pyruvic acid is a yellowish, somewhat thick liquid. 1857Miller Elem. Chem. III. 332 A new acid termed pyruvic or pyroracemic acid. 1873Watts Fownes' Chem. 707 Ordinary lactic acid is also produced..by the action of nascent hydrogen on pyruvic acid. 1927M. Bodansky Introd. Physiol. Chem. ix. 226 There is..no convincing evidence that physiologically lactic acid is converted into pyruvic acid, although the change is known to occur in vitro under the influence of hydrogen peroxide. 1941Adv. Enzymol. I. 147 Even the pyruvic acid oxidase of Bacterium Delbrueckii..might be called a composite thiamin enzyme as it contains flavin adenine nucleotide besides thiamin pyrophosphate, both of which are possibly bound to the same protein. 1945Jrnl. Biol. Chem. CLIX. 543 The pyruvic oxidases of Proteus vulgaris and Escherichia coli do not appear to require inorganic phosphate for activity. 1951Sci. News XXII. 80 An illuminated preparation of spinach chloroplasts can reduce carbon dioxide plus pyruvic acid to malic acid. 1951Sumner & Myrbäck Enzymes II. ii. 1433/1 (Index), Pyruvic kinase. 1962S. G. Waley in A. Pirie Lens Metabolism Rel. Cataract 357 Thiamine (as the pyrophosphate) is the coenzyme in the decarboxylation of the α-keto acids, pyruvic acid and α-ketogluric acid. 1963Conn & Stumpf Outl. Biochem. xi. 201 The conversion of pyruvate to acetyl-CoA is catalyzed by the enzyme complex known as pyruvic oxidase. 1967Batsakis & Briere Interpretive Enzymol. xii. 242 Pyruvic kinase deficiency leads directly to an impairment of ATP synthesis. 1970[see pyruvate 1]. 1971C. J. Gray Enzyme-Catalysed Reactions vii. 291 Porcine pyruvic oxidase catalysed the synthesis of α-acetolactate from pyruvate and the hydroxyethylthiamine pyrophosphate.
Also pyˈruvin, or glycide pyruvate, C6H8O4, a white crystalline substance obtained by distilling glycerin with tartaric acid.
1872Jrnl. Chem. Soc. XXV. 400 When glycerin is heated in a retort with tartaric acid, crystals of pyruvin are formed in the neck of the receiver. |