| 释义 |
pyrazolone Chem.|paɪər-, pɪˈræzələʊn|
[ad. G. pyrazolon (L. Knorr 1887, in Ann. d. Chem. CCXXXVIII. 145): see pyrazole and -one.]
Any keto derivative of a pyrazoline; spec. NH·N:CH·CH2·CO (5-pyrazolone), a weakly acidic white crystalline solid; also, any of their substituted derivatives, several of which on coupling with diazo compounds give rise to commercially important dyestuffs.
1887Jrnl. Chem. Soc. LII. 601 Many of the compounds obtained by the action of ethyl acetoacetate and its derivatives on the primary aromatic hydrazines have already been described by the author as quinizines... The author [sc. Knorr] now regards these substances as pyrazolones. 1926H. G. Rule tr. J. Schmidt's Text-bk. Org. Chem. iii. iii. 566 The oxygen of pyrazolones may also be removed by heating..with phosphorus oxychloride, when chloro-derivatives are formed. 1961G. M. Badger Chem. Heterocyclic Compounds v. 226 Theoretically, there are three types of..pyrazolone, but only derivatives of 3-pyrazolone and of 5-pyrazolone are known. 1968Kirk-Othmer Encycl. Chem. Technol. (ed. 2) XVI. 763 Neither pyrazoles nor pyrazolines have found extensive uses, but pyrazolones have been widely utilized as fabric dyes and pigments, as food coloring agents, in color photography, as photographic developing agents, and as pharmaceuticals. 1977Lancet 23 Apr. 905/1 Reversible agranulocytosis has also been described with pyrazolone derivatives (such as phenylbutazone). |